PZ0247

PF-04979064

≥98% (HPLC)

• 别名: 1,3-Dihydro-1-[1-[(2S)-2-hydroxy-1-oxopropyl]-4-piperidinyl]-3-methyl-8-(6-methyl-3-pyridinyl)-2H-imidazo[4,5-c][1,5]naphthyridin-2-one
• 经验公式（希尔记法）: C₂₄H₂₆N₆O₃
• CAS号: 1220699-06-8
• 分子量: 446.50
• MDL编号: MFCD28155091
• UNSPSC代码: 12352200
• NACRES: NA.77

属性

• 质量水平: 100
• 方案: ≥98% (HPLC)
• 表单: powder
• 颜色: white to beige
• 溶解性: DMSO: 2 mg/mL, clear (warmed)
• 储存温度: room temp
• SMILES字符串: CN(C(N1C2CCN(C([C@@H](O)C)=O)CC2)=O)C3=C1C4=NC(C5=CN=C(C)C=C5)=CC=C4N=C3
• InChI: 1S/C24H26N6O3/c1-14-4-5-16(12-25-14)18-6-7-19-21(27-18)22-20(13-26-19)28(3)24(33)30(22)17-8-10-29(11-9-17)23(32)15(2)31/h4-7,12-13,15,17,31H,8-11H2,1-3H3/t15-/m0/s1
• InChI key: GACQNUHFDBEIQH-HNNXBMFYSA-N

说明

生化/生理作用

PF-04979064 is a highly potent and selective PI3K/mTOR dual kinase inhibitor.

PF-04979064 is an orally available, potent and selective PI3K/mTOR dual kinase inhibitor that potently inhibits tumor growth in mouse xenografts.

安全信息

• 象形图: GHS06
• 警示用语：: Danger
• 危险声明: H301
• 预防措施声明: P264 - P270 - P301 + P310 - P405 - P501
• 危险分类: Acute Tox. 3 Oral
• 储存分类代码: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable