ARF-BP1, ARF-binding protein 1, BJ-HCC-24 tumor antigen, HECT, HECT domain protein LASU1, HECTH9, HSPC272, Ib772, KIAA0312, LASU1, MULE, Mcl-1 ubiquitin ligase E3, UBA and WWE domain containing 1, UBA and WWE domain-containing protein 1, URE-B1, URE-binding protein 1, UREB1, homologous to E6AP carboxyl terminus homologous protein 9, large structure of UREB1, upstream regulatory element-binding protein 1
The epitope recognized by PLA0111 maps to a region between residues 1025 and 1075 of human Upstream Regulatory Element Binding Protein 1 using the numbering given in entry NP_113584.2 (GeneID 10075).
外形
Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
其他说明
The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Lasu1/Ureb1 is an E3 ubiquitin protein ligase that mediates the ubiquitination of core histones, Mcl-1, Cdc6, and p53. Lasu1/Ureb1 expression is regulated during spermatogenesis and appears to play a role in chromatin modification in germ cells as well as other tissues.
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