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Merck

P3761

Sigma-Aldrich

戊巴比妥 钠盐

别名:

5-乙基-5-(1-甲基丁基)-2,4,6-三氧六氢嘧啶, 戊巴比妥

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About This Item

经验公式(希尔记法):
C11H17N2NaO3
CAS号:
分子量:
248.25
EC號碼:
MDL號碼:
分類程式碼代碼:
41116107
PubChem物質ID:

形狀

powder

品質等級

藥物控制

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

溶解度

H2O: soluble
alcohol: soluble

SMILES 字串

[Na].CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3.Na.H/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);;

InChI 密鑰

PGOYUXGHADTNIB-UHFFFAOYSA-N

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應用

戊巴比妥钠盐在各种体外研究之前被用作大鼠和小鼠的麻醉剂。

生化/生理作用

戊巴比妥(PB)是一种巴比妥酸盐,是γ-氨基丁酸亚型A (GABAA)受体的配体。它是一种镇静麻醉剂,主要用于啮齿动物安乐死。戊巴比妥具有催眠功能和放松肌肉的特性。它能增强氨基丁酸能活性。腹腔注射PB可导致右立反射(LORR)丧失和心跳停止。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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