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Merck
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文件

N9007

Supelco

诺司卡品 盐酸盐 水合物

analytical standard

别名:

那可汀 盐酸盐

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About This Item

经验公式（希尔记法）:
C22H23NO7 · HCl · xH2O
CAS号:
912-60-7
分子量:
449.88 (anhydrous basis)
EC號碼:
213-014-9
MDL號碼:
MFCD00149223
分類程式碼代碼:
41116107
PubChem物質ID:
329818691
NACRES:
NA.24

等級

analytical standard

品質等級

100

技術

HPLC: suitable
gas chromatography (GC): suitable

mp

221-223 °C (lit.)

應用

food and beverages

格式

neat

儲存溫度

2-8°C

SMILES 字串

O.Cl.COc1ccc2C(OC(=O)c2c1OC)C3N(C)CCc4cc5OCOc5c(OC)c34

InChI

1S/C22H23NO7.ClH.H2O/c1-23-8-7-11-9-14-20(29-10-28-14)21(27-4)15(11)17(23)18-12-5-6-13(25-2)19(26-3)16(12)22(24)30-18;;/h5-6,9,17-18H,7-8,10H2,1-4H3;1H;1H2/t17-,18+;;/m1../s1

InChI 密鑰

ZYGSNVAGWKWKKI-WCRQIBMVSA-N

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應用

Noscapine hydrochloride hydrate may be used as a reference standard in the determination of noscapine hydrochloride in the synthetic binary mixtures like chlorpheniramine-noscapine and chlorpheniramine-guaiphenesin using derivative spectrophotometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

象形圖

Exclamation mark
GHS07

訊號詞

Warning

危險聲明

H302,H336

防範說明

P301 + P312 + P330

危險分類

Acute Tox. 4 Oral - STOT SE 3

標靶器官

Central nervous system

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
0000309816
0000234662
0000191750
SLCH3288
SLCB6101

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Rapid and accurate determination of chlorpheniramine maleate, noscapine hydrochloride and guaiphenesin in binary mixtures by derivative spectrophotometry.
Pappano B N, et al.
Talanta, 44(4), 633-639 (1997)
Patricia López et al.
Food chemistry, 242, 443-450 (2017-10-19)
A straightforward method to determine the content of six opium alkaloids (morphine, codeine, thebaine, noscapine, papaverine and narceine) in poppy seeds and bakery products was developed and validated down to a limit of quantification (LOQ) of 0.1mg/kg. The method was
Ana Amaral et al.
International journal of molecular sciences, 22(10) (2021-06-03)
Endometrosis is a reproductive pathology that is responsible for mare infertility. Our recent studies have focused on the involvement of neutrophil extracellular traps enzymes, such as elastase (ELA), in the development of equine endometrosis. Noscapine (NOSC) is an alkaloid derived
Ana Amaral et al.
Life (Basel, Switzerland), 11(10) (2021-10-24)
Cathepsin G (CAT) is a protease released by neutrophils when forming neutrophil extracellular traps that was already associated with inducing type I collagen (COL1) in equine endometrium in vitro. Endometrosis is a fibrotic condition mainly characterized by COL1 deposition in
Srinivasa M Sammeta et al.
Pharmaceutical development and technology, 20(2), 169-175 (2013-11-14)
The main objective of the present study was to develop formulations of noscapine hydrochloride hydrate with enhanced solubility and bioavailability using co-solvent- and cyclodextrin-based approaches. Different combinations of co-solvents, which were selected on the basis of high-throughput solubility screening, were

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