推荐产品
生物源
synthetic (organic)
化驗
≥97%
形狀
powder
顏色
white to off-white
mp
145-148 °C
溶解度
DMSO: 50 mg/mL
SMILES 字串
O=[As]c1ccccc1
InChI
1S/C6H5AsO/c8-7-6-4-2-1-3-5-6/h1-5H
InChI 密鑰
BQVCCPGCDUSGOE-UHFFFAOYSA-N
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一般說明
苯氧化砷(PhAsO4)是一种双功能SH基化学物质。它本质上是疏水的。
應用
苯氧化砷已被用于通过黑质纹状体横断进行动物灌注,以确定过氧钒(pVa)是否会与脑源性神经营养因子(BDNF)协同作用。
生化/生理作用
苯氧化砷(PAO)可降低狗尾草的活力和可持续性。在EGTA(乙二醇-双(β-氨基乙基醚)N,N,N′,N′-)的存在下,它具有刺激环孢菌素A敏感型转化的能力。它可作为线粒体离子通量的一种刺激因子。
氧化苯胂可抑制细胞表面受体的内在化;抑制酪氨酸磷酸酶,且对酪氨酸激酶无影响。代谢毒物。
特點和優勢
《受体分类和信号转导》手册的 磷蛋白磷酸酶(酪氨酸) 页面有该化合物的介绍。想要浏览手册的其他页面, 请单击此处。
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
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Regulation of epithelial and endothelial permeability is essential for proper function of compartmentalized organisms, and tyrosine phosphorylation plays an important role in this process. We analyzed the impact of protein tyrosine phosphatase (PTP) inhibition on the structure of endothelial junctional
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Journal of Bioenergetics and Biomembranes, 23(4), 679-688 (1991)
Tyrosine phosphatase inhibition enhances neurotrophin potency and rescues nigrostriatal neurons in adult rats
Experimental neurology, 178(2), 259-267 (2002)
Inhibition of setaria cervi protein tyrosine phosphatases by phenylarsine oxide: A proteomic and biochemical study
Acta Tropica, 159, 20-28 (2016)
Nature plants, 6(5), 544-555 (2020-05-13)
The 3-phosphoinositide-dependent protein kinase 1 (PDK1) is a conserved master regulator of AGC kinases in eukaryotic organisms. pdk1 loss of function causes a lethal phenotype in animals and yeasts, but only mild phenotypic defects in Arabidopsis thaliana (Arabidopsis). The Arabidopsis genome
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