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Merck
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主要文件

P0883

Sigma-Aldrich

聚(脱氧腺苷-胸苷)酸 钠盐

double-stranded alternating copolymer

别名:

Poly(dA-dT) • Poly(dA-dT)

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10 UNITS
$454.00
25 UNITS
$943.00
50 UNITS
$1,700.00

$454.00


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10 UNITS
$454.00
25 UNITS
$943.00
50 UNITS
$1,700.00

About This Item

CAS号:
MDL编号:
UNSPSC代码:
41106305
NACRES:
NA.51

$454.00


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表单

powder

储存温度

−20°C

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应用

聚(脱氧腺苷-胸苷)(Poly(dA-dT) • Poly(dA-dT))酸是用于DNA结构动力学和药物相互作用的构象研究的双链交替共聚物DNA模型。

其他说明

双链交替共聚物。

单位定义

一个酶活性单位是指在pH 7.0(1cm光程)条件下,在1.0 ml 20 mM磷酸钠/100 mM NaCl中产生1.0的A260 所需的酶量。

数量

1 mg相当于 ≥12 A260 单位。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Marta Airoldi et al.
Journal of biomolecular structure & dynamics, 25(1), 77-84 (2007-08-07)
The thermal denaturation of the synthetic high molecular weight double stranded polynucleotide poly(dA-dT) x poly(dA-dT) has been studied in aqueous buffered solution (Tris 1.0 mM; pH 7.8+/-0.2) in the presence of increasing concentrations of either Ni(2+) (borderline cation) or Cd(2+)
M Vorlícková et al.
Journal of biomolecular structure & dynamics, 3(1), 67-83 (1985-08-01)
The article reviews data indicating that poly(dA-dT).poly(dA-dT) is able of adopting three distinct double helical structures in solution, of which only the A form conforms to classical notions. The other two structures have dinucleotides as double helical repeats. At low
Marta Airoldi et al.
Chirality, 20(9), 951-960 (2008-02-05)
The thermal behavior of the synthetic, high molecular weight, double stranded polynucleotides poly(dA-dT).poly(dA-dT) [polyAT] and poly(dG-dC).poly(dG-dC) [polyGC] solubilized in the aqueous core of the quaternary water-in-oil cationic microemulsion CTAB|n-pentanol|n-hexane|water in the presence of increasing amounts of NiCl(2) at several constant
Natasha McStay et al.
Nucleic acids research, 45(2), 527-540 (2016-12-03)
Herein we report the synthesis of tripodal C
Creina Slator et al.
ACS chemical biology, 11(1), 159-171 (2015-10-22)
The in cellulo catalytic production of reactive oxygen species (ROS) by copper(II) and iron(II) complexes is now recognized as a major mechanistic model in the design of effective cytotoxins of human cancer. The developmental complex, [Cu(o-phthalate)(1,10-phenanthroline)] (Cu-Ph), was recently reported

Questions

1–4 of 4 Questions  
  1. What is the difference between Poly(deoxyadenylic-thymidylic) acid sodium salt Products P0883 and P5782?

    1 answer
    1. Prod. No. P0883 is from a different supplier than Prod. No. P5782.  Chain lengths for both products can vary from batch to batch.  According to information from our suppliers, the A250/A260 ratios are similar, but the A280/A260 ratio for Prod. No. P0883 will be slightly higher than that of Prod. No. P5782.

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  2. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  3. What is the sequence of Product P0883, Poly(deoxyadenylic-thymidylic) acid sodium salt?

    1 answer
    1. This product is a double-stranded alternating DNA copolymer, although it is possible for single strands to be present.  The sequence of each strand is an alternating sequence of dAdTdAdTdAdT….. or dATdATdATdAT… since dT (deoxythymidylic acid) and T (thymidylic acid) are the same.

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  4. In what should Product P0883, Poly(deoxyadenylic-thymidylic) acid sodium salt, be dissolved?

    1 answer
    1. Per our supplier, to maintain a double stranded configuration of the polymer in solution, it should be rehydrated with a neutral buffer containing 100 mM NaCl.  After reconstitution, the polymer solution should be stored at -20°C.

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