推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
lyophilized powder
物種活性
human, rat
技術
western blot (chemiluminescent): 1:200 using rat brain membranes
UniProt登錄號
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
rat ... Kcnn2(54262)
一般說明
Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 is expressed in rat Purkinje cells. The gene encoding this protein is localized on rat chromosome 18q11.
免疫原
synthetic peptide corresponding to amino acids 542-559 of rat potassium channel SK2.
應用
Anti-Potassium Channel SK2 (Apamin-Sensitive Conductance Ca2+-Dependent K+ Channel, KCa2, Kcnn2, SKCa2) antibody produced in rabbit has been used for immunohistochemistry and immunofluorescence.
生化／生理作用
Potassium calcium-activated channel subfamily N member 2 (KCNN2) or SK2 has a role in the modulation of intrinsic excitability of neurons and Purkinje cells. It also has a role in synaptic transmission and plasticity. SK2 promotes hippocampus-dependent learning and memory in the mammalian brain.
外觀
Lyophilized at 0.3-1.4 mg/mL from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.025% - 0.050% sodium azide.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Low-Level Vagus Nerve Stimulation Upregulates Small Conductance Calcium Activated Potassium Channels in the Stellate Ganglion
Mark J. Shen
Heart Rhythm : the Official Journal of the Heart Rhythm Society (2013)
Neurotransmitter modulation of small conductance Ca2+-activated K+ (SK) channels by regulation of Ca2+ gating
Francois M
Neuron (2008)
Jing-Yi Jeng et al.
The Journal of physiology, 598(18), 3891-3910 (2020-07-02)
Age-related hearing loss (ARHL) is a very heterogeneous disease, resulting from cellular senescence, genetic predisposition and environmental factors (e.g. noise exposure). Currently, we know very little about age-related changes occurring in the auditory sensory cells, including those associated with the
Eleonora Katz et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 24(36), 7814-7820 (2004-09-10)
In the mature cochlea, inner hair cells (IHCs) transduce acoustic signals into receptor potentials, communicating to the brain by synaptic contacts with afferent fibers. Before the onset of hearing, a transient efferent innervation is found on IHCs, mediated by a
Deletion of the Ca2+-activated potassium (BK) a-subunit but not the BK?1-subunit leads to progressive hearing loss
Lukas Ruttiger
Proceedings of the National Academy of Sciences of the USA (2004)
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