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Merck

P0100

Sigma-Aldrich

Psilocybin

≥98% (HPLC), solid

别名:

3-[2-(Dimethylamino)ethyl]-1H-indol-4-yl phosphate

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About This Item

经验公式(希尔记法):
C12H17N2O4P
CAS号:
分子量:
284.25
EC 号:
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77

方案

≥98% (HPLC)

表单

solid

药品控制

USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada

溶解性

H2O: >20 mg/mL

储存温度

−20°C

SMILES字符串

CN(C)CCc1c[nH]c2cccc(OP(O)(O)=O)c12

生化/生理作用

Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic.
Psilocybin is a hallucinogenic serotonin 1A and 2A agonist and psychotomimetic. It is the minor hallucinogenic component of Teonanácatl, the sacred mushroom of Mexico. Psilocybin produces muscle relaxation, dilation of pupils, vivid visual and auditory distortions, and emotional disturbances.

象形图

Health hazardExclamation mark

警示用语:

Danger

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Matthew W Johnson et al.
Drug and alcohol dependence, 123(1-3), 132-140 (2011-12-02)
Psilocybin is a well-characterized classic hallucinogen (psychedelic) with a long history of religious use by indigenous cultures, and nonmedical use in modern societies. Although psilocybin is structurally related to migraine medications, and case studies suggest that psilocybin may be efficacious
Michael Kometer et al.
Biological psychiatry, 72(11), 898-906 (2012-05-15)
Serotonin (5-HT) 1A and 2A receptors have been associated with dysfunctional emotional processing biases in mood disorders. These receptors further predominantly mediate the subjective and behavioral effects of psilocybin and might be important for its recently suggested antidepressive effects. However
Robin L Carhart-Harris et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(6), 2138-2143 (2012-02-07)
Psychedelic drugs have a long history of use in healing ceremonies, but despite renewed interest in their therapeutic potential, we continue to know very little about how they work in the brain. Here we used psilocybin, a classic psychedelic found
Jonathan P Roiser et al.
Current biology : CB, 22(7), R231-R233 (2012-04-14)
Two recent studies report changes in human brain responses after exposure to psilocybin, the active ingredient of hallucinogenic mushrooms. Psilocybin increased sensory cortex responses during emotional recollection, but decreased resting-state blood flow in prefrontal cortex, with potential implications for treating depression.
Erich Studerus et al.
PloS one, 7(2), e30800-e30800 (2012-03-01)
Responses to hallucinogenic drugs, such as psilocybin, are believed to be critically dependent on the user's personality, current mood state, drug pre-experiences, expectancies, and social and environmental variables. However, little is known about the order of importance of these variables

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