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Merck
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文件

N7252

Sigma-Aldrich

19-去甲睾酮

别名:

17β-羟基-19-去甲雄甾-4-烯-3-酮, 17β-羟基-4-雌烯-3-酮, 19-去甲雄甾烯醇酮, 4-雌烯-17β-醇-3-酮, Nadrolone, 诺龙

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About This Item

经验公式（希尔记法）:
C18H26O2
CAS号:
434-22-0
分子量:
274.40
Beilstein:
2055849
EC號碼:
207-101-0
MDL號碼:
MFCD00003664
分類程式碼代碼:
51111800
PubChem物質ID:
24897817
NACRES:
NA.77

生物源

synthetic (organic)

品質等級

200

無菌

non-sterile

化驗

≥98% (TLC)

形狀

powder

藥物控制

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

溶解度

chloroform: 50 mg/mL, clear, colorless to light yellow

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@H]2O

InChI

1S/C18H26O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h10,13-17,20H,2-9H2,1H3/t13-,14+,15+,16-,17-,18-/m0/s1

InChI 密鑰

NPAGDVCDWIYMMC-IZPLOLCNSA-N

基因資訊

human ... SERPINA6(866) , SHBG(6462)
rat ... Ar(24208) , Nr3c2(25672) , Pgr(25154)

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生化／生理作用

19-Nortestosterone (nandrolone) is an anabolic steriod hormone that acts as an androgen receptor (AR) agonist.

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H351,H360FD

危險分類

Carc. 2 - Repr. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves

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P Kintz et al.
Journal of pharmaceutical and biomedical analysis, 24(5-6), 1125-1130 (2001-03-15)
A sensitive, specific and reproducible method for the quantitative determination of nandrolone in human hair has been developed. The sample preparation involved a decontamination step of the hair with methylene chloride. The hair sample (about 100 mg) was solubilized in
Pieter Van Renterghem et al.
Analytica chimica acta, 768, 41-48 (2013-03-12)
Due to their performance enhancing properties, use of anabolic steroids (e.g. testosterone, nandrolone, etc.) is banned in elite sports. Therefore, doping control laboratories accredited by the World Anti-Doping Agency (WADA) screen among others for these prohibited substances in urine. It
R M N Kohler et al.
British journal of sports medicine, 36(5), 325-329 (2002-09-28)
The aim of this review is to analyse the studies on nandrolone metabolism to determine if it is possible for an athlete to test positive for nandrolone without having ingested or injected nandrolone.
A Farjam et al.
Analytical chemistry, 63(21), 2481-2487 (1991-11-01)
An immunoaffinity precolumn containing immobilized antibodies raised against the synthetic steroid hormone beta-19-nortestosterone, has been used for the automated sample pretreatment of urine samples containing beta-19-nortestosterone or the related steroids norethindrone and norgestrel. The sample pretreatment system was coupled on-line
Katrien Venken et al.
Bone, 36(4), 663-670 (2005-03-24)
This study reports the preclinical evaluation of the bone and muscle protective potential of the synthetic androgen 7alpha-methyl-19-nortestosterone (MENTtrade mark), as assessed in the aged orchidectomized rat model. Aged (13-month-old) orchidectomized Wistar rats were treated with different doses of MENT
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