Anti-Nerve Growth Factor 2.5S, catalog number N6655, is produced in rabbits using immunogen 2.5S nerve growth factor purified from mouse submaxillary glands.
价格与库存信息目前不能提供
推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
fractionated antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
mouse, human
技术
Ouchterlony double diffusion: suitable
western blot: 1:2,000
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... NGF(4803)
mouse ... Ngf(18049)
一般描述
神经生长因子(NGF)属于神经营养蛋白家族。它位于人类染色体上的1p13.2。NGF有两种分子形式，即7S NGF和2.5S NGF，它们对神经元具有相同的神经营养作用。
特异性
可用于监测NGF（2.5S、β和7S）。
免疫原
来自雄性小鼠颌下腺的NGF-2.5S。
应用
抗神经生长因子2.5S抗体可用于免疫印迹和斑点印迹，最低抗体工作稀释度为1:2000。使用大鼠中缝大核组织提取物将1:1000的抗体稀释液用于免疫印迹。该抗体用于小鼠星形胶质细胞的免疫荧光和中和测定。
生化/生理作用
该基因的突变导致遗传性感觉和自主神经病变第五类（HSAN-V）。
外形
磷酸盐缓冲盐水溶液。
免责声明
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Liang-Wei Chen et al.
The Journal of comparative neurology, 497(6), 898-909 (2006-06-28)
To address the hypothesis that reactive astrocytes in the basal ganglia of an animal model of Parkinson's disease serve neurotrophic roles, we studied the expression pattern of neurotrophic factors in the basal ganglia of C57/Bl mice that had been treated
New protein fold revealed by a 2.3-
McDonald N Q, et al.
Nature, 354(6352), 411-411 (1991)
Micaela Caserta et al.
Frontiers in neuroscience, 13, 58-58 (2019-02-23)
Previous studies demonstrated exercise-induced modulation of neurotrophins, such as Nerve Growth Factor (NGF) and Brain-Derived Neurotrophic Factor (BDNF). Yet, no study that we are aware of has examined their change as a function of different training paradigms. In addition, the
7S nerve growth factor has different biological activity from 2.5 S nerve growth factor in vitro
Shao N, et al.
Brain Research, 609(1-2), 338-340 (1993)
Bihua Bie et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 30(16), 5617-5628 (2010-04-23)
Sorting of intracellular G-protein-coupled receptors (GPCRs) either to lysosomes for degradation or to plasma membrane for surface insertion and functional expression is a key process regulating signaling strength of GPCRs across the plasma membrane in adult mammalian cells. However, little
-
Is this antibody N6655 anti-NGF 2.5S against targeting NGFR?
1 answer-
Helpful?
-
-
What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Helpful?
-
-
In western blot application, what size protein is recognized by Product N6655, Anti-Nerve Growth Factor 2.5S antibody produced in rabbit?
1 answer-
Product N6655, Anti-Nerve Growth Factor 2.5S antibody produced in rabbit, will recognize a 30 kD protein on western blot.
Helpful?
-
-
How does the storage temperature relate to shipping conditions?
1 answer-
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.
Helpful?
-
Active Filters
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门
