跳转至内容
Merck

MAK110

Sigma-Aldrich

MTP 活性检测试剂盒

Supplied by Roar Biomedical, Inc.

别名:

MTTP活性检测试剂盒, 微粒体甘油三酯转运蛋白活性检测试剂盒

登录查看公司和协议定价


About This Item

分類程式碼代碼:
12161503
NACRES:
NA.84

用途

sufficient for 100 fluorometric tests

應用

pharmaceutical

檢測方法

fluorometric

相關疾病

cardiovascular diseases

儲存溫度

2-8°C

基因資訊

human ... MTTP(4547)

一般說明

微粒体甘油三酯转移蛋白(MTP),一种存在于肝脏中的膜结合蛋白,可在极低密度脂蛋白(VLDL)的组装和分泌中起到重要作用。MTP对于肠内乳糜微粒的组装和分泌也是必需的。该蛋白有助于甘油三酯(TG)、胆固醇酯(CE)和磷脂酰胆碱(PC)在磷脂表面之间的转移。 MTP基因中的突变可导致无β脂蛋白血症。

應用

MTP活性检测试剂盒已被用于测量微粒体甘油三酯转移蛋白(MTP)的活性。

特點和優勢

兼容高通量操作系统。

適合性

适用于测量细胞裂解液或组织匀浆液中微粒体[甘油三酯]转移蛋白(MTP)的活性,或用于筛选MTP活性抑制剂。

原則

MTP活性检测试剂盒是一种灵敏的均质荧光检测方法,可用于细胞裂解物或组织匀浆中中MTP活性的连续测量。该试剂盒包括能够检测 MTP 介导的中性脂质转移的专有底物。 这种转移活性导致荧光强度增加(λEx=465 nm/λEm=535 nm)。

推薦

产品编号
说明
价格

相關產品

产品编号
说明
价格

儲存類別代碼

10 - Combustible liquids


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

其他客户在看

Slide 1 of 2

1 of 2

Thi Thu Trang Tran et al.
The Journal of biological chemistry, 291(31), 16328-16338 (2016-06-04)
The worldwide prevalence of metabolic diseases is increasing, and there are global recommendations to limit consumption of certain nutrients, especially saturated lipids. Insulin resistance, a common trait occurring in obesity and type 2 diabetes, is associated with intestinal lipoprotein overproduction.
J Massart et al.
British journal of pharmacology, 165(5), 1361-1374 (2011-07-12)
Pentoxifylline is in clinical trials for non-alcoholic fatty liver disease and diabetic nephropathy. Metabolic and hepatic effects of pentoxifylline were assessed in a murine model of obesity and type 2 diabetes. Pentoxifylline (100 mg·kg(-1) ·day(-1)) was administered for 4 days
Qinyuan Ye et al.
Hepatology research : the official journal of the Japan Society of Hepatology, 43(10), 1115-1123 (2013-02-21)
To investigate the role of Cytochrome P4502E1 in sensitizing Kupffer cells to lipopolysaccharide (LPS)-mediated inflammation after ethanol induction. Sprague-Dawley rats were fed a liquid ethanol diet, control diet or ethanol diet supplemented with CYP2E1 inhibitor, chlormethiazole (CMZ), for 4 weeks. Hepatic
Short-term palmitate supply impairs intestinal insulin signaling via ceramide production.
Tran T T T, et al.
The Journal of Biological Chemistry, M115-M115 (2016)
Yuan-Lung Cheng et al.
Clinical science (London, England : 1979), 125(9), 439-448 (2013-05-11)
HCV (hepatitis C virus) infection affects an estimated 180 million people in the world's population. Adverse effects occur frequently with current standard treatment of interferon and ribavirin, while resistance of new direct anti-viral agents, NS3 protease inhibitors, is a major

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门