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用途
sufficient for 100 fluorometric tests
應用
pharmaceutical
檢測方法
fluorometric
相關疾病
cardiovascular diseases
儲存溫度
2-8°C
基因資訊
human ... MTTP(4547)
一般說明
微粒体甘油三酯转移蛋白(MTP),一种存在于肝脏中的膜结合蛋白,可在极低密度脂蛋白(VLDL)的组装和分泌中起到重要作用。MTP对于肠内乳糜微粒的组装和分泌也是必需的。该蛋白有助于甘油三酯(TG)、胆固醇酯(CE)和磷脂酰胆碱(PC)在磷脂表面之间的转移。 MTP基因中的突变可导致无β脂蛋白血症。
應用
MTP活性检测试剂盒已被用于测量微粒体甘油三酯转移蛋白(MTP)的活性。
特點和優勢
兼容高通量操作系统。
適合性
适用于测量细胞裂解液或组织匀浆液中微粒体[甘油三酯]转移蛋白(MTP)的活性,或用于筛选MTP活性抑制剂。
原則
MTP活性检测试剂盒是一种灵敏的均质荧光检测方法,可用于细胞裂解物或组织匀浆中中MTP活性的连续测量。该试剂盒包括能够检测 MTP 介导的中性脂质转移的专有底物。 这种转移活性导致荧光强度增加(λEx=465 nm/λEm=535 nm)。
儲存類別代碼
10 - Combustible liquids
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