推荐产品
品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white
溶解度
deionized water: ≥20 mg/mL
儲存溫度
room temp
SMILES 字串
[Cl-].CC1OC(CC1O)C[N+](C)(C)C
InChI
1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1
InChI 密鑰
WUFRNEJYZWHXLC-UHFFFAOYSA-M
基因資訊
human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)
應用
(±)-Muscarine chloride hydrate may be used:
- as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
- as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments
- as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples
生化／生理作用
Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.
Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.
特點和優勢
This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Eye Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
P J FRASER
British journal of pharmacology and chemotherapy, 12(1), 47-52 (1957-03-01)
The action of chromatographically pure crystalline muscarine chloride, prepared from Amanita muscaria, has been compared with acetylcholine chloride (ACh) on a number of different organs from a variety of species. Muscarine caused spasm in vivo and in vitro of muscles
Chapter 67 - Mushroom Toxins
Puschner B
Veterinary Toxicology, 955-966 (2018)
Two-dimensional surface plasmon resonance imaging system for cellular analysis
Biosensors and Biodetection, 12(1), 47-52 (2017)
Thomas P Bambauer et al.
Talanta, 204, 677-684 (2019-07-31)
Paper spray mass spectrometry (PSMS) is currently used in different analytical fields, but less effort has been made so far to use PSMS for highly polar compounds. Such analytes usually show poor performance in PSMS due to their high affinity
Thomas P Bambauer et al.
Talanta, 213, 120847-120847 (2020-03-24)
The analytical proof of a toxic mushroom and/or plant ingestion at an early stage of a suspected intoxication can be crucial for fast therapeutic decision making. Therefore, comprehensive analytical procedures need to be available. This study aimed to develop a
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