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一般說明
化合物以 96 孔格式排列在 16 个 80 的管架中，每个孔一个化合物（25 μl，10 mM，DMSO 溶液，在存档存储架中）。
應用
药理活性化合物数据库（LOPAC）®1280 - 小规模已被用于筛查氯硝柳胺和尼日利亚菌素诱发的白细胞介素（IL-1β) 释放抑制剂。
特點和優勢
包括细胞信号& 神经科学领域中最新的类药物分子 ：
- 细胞凋亡
- G 蛋白 & 环核苷酸
- 基因调控 & 表达
- 离子通道
- 脂质信号
- 多重耐药性
- 神经传递
- 磷酸化
提供 SDFile 来构建包含以下内容的数据库：
- 结构
- 主要名称
- 次要名称
- 药理活性
- 货号
- 管架位置
其他說明
仅限美国境外销售。美国客户应参考货号 LO4100。
法律資訊
LOPAC is a registered trademark of Merck KGaA, Darmstadt, Germany
訊號詞
Danger
危險分類
Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1A - Eye Dam. 1 - Lact. - Muta. 1B - Repr. 1A - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT RE 2 - STOT SE 2
儲存類別代碼
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
閃點（°F）
188.6 °F
閃點（°C）
87 °C
其他客户在看
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High genetic and phenotypic variability between Leishmania species and strains within species make the development of broad-spectrum antileishmanial drugs challenging. Thus, screening panels consisting of several diverse Leishmania species can be useful in enabling compound prioritization based on their spectrum
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Tran UT and Kitami T
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High-throughput screening identifies compounds that enhance lentiviral transduction.
Johnston JM, Denning G, Moot R, et al.
Gene Therapy, doi:10-doi:10 (2014)
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Methylated DNA binding proteins such as Methyl-CpG Binding Domain Protein 2 (MBD2) can transduce DNA methylation alterations into a repressive signal by recruiting transcriptional co-repressor complexes. Interfering with MBD2 could lead to reactivation of tumor suppressor genes and therefore represents
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