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质量水平
方案
≥98% (HPLC)
表单
powder
溶解性
DMSO: >20 mg/mL
储存温度
2-8°C
SMILES字符串
CC(Sc1nc2ccccc2[nH]1)C(=O)N\N=C\c3cc(Br)ccc3O
InChI
1S/C17H15BrN4O2S/c1-10(25-17-20-13-4-2-3-5-14(13)21-17)16(24)22-19-9-11-8-12(18)6-7-15(11)23/h2-10,23H,1H3,(H,20,21)(H,22,24)/b19-9+
InChI key
WILMXUAKQKGGCC-DJKKODMXSA-N
应用
生化/生理作用
KH7 是可溶性腺苷酸环化酶的选择性抑制剂。
KH7 是可溶性腺苷酸环化酶的选择性抑制剂。可溶性腺苷酸环化酶（sAC）泛表达，是cAMP 信号传递的重要组成部分。
特点和优势
这种化合物是环核苷酸研究的特色产品。点击此处查看更多特色环核苷酸产品。登录sigma.com/discover-bsm可了解更多关于其他研究领域中关于生物活性小分子的消息。
适用性
在洗涤剂的作用下，KH7 对 sAC 无活性。当用于细胞实验时，KH7 在50μM以上的浓度下显示出非特异性膜破坏效应。
警示用语：
Danger
危险声明
危险分类
Acute Tox. 3 Oral
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
其他客户在看
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Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 191(1), 113-125 (2020-11-21)
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商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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