HSTUD0382

MISSION^® Synthetic microRNA Inhibitor, Human

hsa-miR-216b

• UNSPSC代码: 12352200
• NACRES: NA.51

属性

• 产品线: MISSION^®
• 表单: solid
• 成熟序列: AAAUCUCUGCAGGCAAAUGUGA
• Sanger mature/minor 登记号: MIMAT0004959
• Sanger microRNA登记号: MI0005569
• 储存温度: −20°C

说明

一般描述

Individual synthetic microRNA inhibitors were designed using a proprietary algorithm, which is based on the work of Haraguchi, T, et al. and in collaboration with Dr. Hideo Iba, University of Tokyo.[1] This algorithm utilizes the tough decoy (TuD) design. miRNA are known to regulate gene expression in a variety of manners, including translational repression, mRNA cleavage and deadenylation.

The MISSION synthetic miRNA Inhibitors are small, double-stranded RNA molecules designed to inhibit a specific mature miRNA. The miRNA inhibitors were designed using the mature miRNA sequence information from miRBase and are 2′-O-methylated RNA duplexes with a miRNA binding site on each strand. Optimal miRNA inhibition is provided after transfection due to the robust secondary structure of the inhibitor.

• Long lasting inhibition at very low dosage
• Excellent resistance to cellular nucleases
• Custom synthesis available for a variety of species

Two negative controls are available: Arabidopsis thaliana sequence (NCSTUD001) and Caenorhabditis elegans sequence (NCSTUD002)

其他说明

Based on miRBase V19

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形图: GHS08
• 警示用语：: Warning
• 危险声明: H373
• 预防措施声明: P260 - P314 - P501
• 危险分类: STOT RE 2 Inhalation
• 靶器官: Respiratory Tract
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable