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HPA016815

Sigma-Aldrich

抗-ZBTB20 兔抗

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

别名:

抗-含锌指和 BTB 结构域蛋白 20, 抗-树突来源的BTB/POZ锌指蛋白, 抗-锌指蛋白288

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100 μL
$778.00

$778.00

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100 μL
$778.00

About This Item

UNSPSC代码:
12352203
人类蛋白质图谱编号:
HPA016815
NACRES:
NA.41

$778.00

请联系客服了解存货情况

生物来源

rabbit

质量水平

100

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

产品线

Prestige Antibodies® Powered by Atlas Antibodies

表单

buffered aqueous glycerol solution

种属反应性

human

技术

immunofluorescence: 0.25-2 μg/mL
immunohistochemistry: 1:50-1:200

免疫原序列

SVEQQFGPGAARDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITVSNSSDKSVLQQPSVNTSIGQPLPSTQLYLRQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQPAGSGPKPFLFSLPQPLAGQQTQ

UniProt登记号

Q9HC78

运输

wet ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... ZBTB20(26137)

免疫原

锌指和含BTB域蛋白20重组蛋白表位标记标签（PrEST）

应用

由Atlas Antibodies提供技术支持的所有Prestige Antibodies抗体均由人类蛋白质图集(HPA)项目开发和验证，因此受到业内最广泛的表征支持。

人类蛋白质图集项目可以分为三大部分： 人体组织图谱、癌症图谱和人类细胞图谱。在组织和癌症图谱项目支持下产生的抗体已通过对数百种正常和疾病组织的免疫组织化学分析得到了验证，并且通过近期人类细胞图谱项目的努力，许多抗体已经过免疫荧光分析的表征，从而绘制人类蛋白质组图谱，不仅是在组织水平上，现在已经达到亚细胞水平。在人类蛋白质图集项目网站上单击图像库链接，可以查看这些图像和庞大的数据集。我们还提供Prestige Antibodies® 抗体的实验方案和其他有用信息。

特点和优势

Prestige Antibodies®是经过高度表征和广泛验证的抗体，同时还有一个优点是其每个靶标的所有可用表征数据都可以通过位于此页面顶部产品名称下方的人类蛋白质图谱门户进行访问。Prestige Antibodies®对其他蛋白质的独特性和低交叉反应性是通过严密的抗原区域选择、亲和纯化和严格的选择来实现的。每种Prestige 抗体都有相应的Prestige 抗原对照品，可在链接部分找到。

每种Prestige 抗体的检测方法如下：
  • 44种正常人体组织和20种最常见癌症组织的IHC组织阵列。
  • 364个人重组蛋白片段的蛋白阵列。

联系

相应抗原APREST73760

外形

磷酸盐缓冲盐水溶液，pH 7.2，含有40%甘油和0.02%叠氮化钠

法律信息

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
R06599
A69412

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Daijiro Konno et al.
Development (Cambridge, England), 146(15) (2019-08-03)
The spatiotemporal identity of neural progenitors and the regional control of neurogenesis are essential for the development of cerebral cortical architecture. Here, we report that mammalian DM domain factors (Dmrt) determine the identity of cerebral cortical progenitors. Among the Dmrt
Anton B Tonchev et al.
Molecular brain, 9(1), 65-65 (2016-06-11)
During corticogenesis, genetic programs encoded in progenitor cells at different developmental stages and inherited in postmitotic neurons specify distinct layer and area identities. Transcription factor Zbtb20 has been shown to play a role for hippocampal development but whether it is
Dimo S Stoyanov et al.
Genes, 13(9) (2022-09-24)
The Zbtb20 gene encodes for a transcription factor that plays an important role in mammalian cortical development. Recently, its expression was reported in the adult mouse subventricular zone (SVZ), a major neurogenic niche containing neural stem cells throughout life. Here
Taisuke Kadoshima et al.
Methods in molecular biology (Clifton, N.J.), 1597, 1-16 (2017-04-01)
In the developing embryo, telencephalon arises from the rostral portion of the neural tube. The telencephalon further subdivides into distinct brain regions along the dorsal-ventral (DV) axis by exogenous patterning signals. Here, we describe a protocol for in vitro generation
Quan Wu et al.
Nature communications, 13(1), 470-470 (2022-01-27)
The cerebral cortex is formed by diverse neurons generated sequentially from neural stem cells (NSCs). A clock mechanism has been suggested to underlie the temporal progression of NSCs, which is mainly defined by the transcriptome and the epigenetic state. However
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Questions

1–2 of 2 Questions  

  1. Is this antibody suitable for Immunofluorescense experiments performed in mouse cryosections previously treated with PFA as a fixative solution?

    1 answer

    1. This product is suitable for immunofluorescence in PFA-fixed tissues, however, the species reactivity is human. This is a product of Atlas Antibodies. The supplier reports an interspecies antigen sequence identity of 91% for mouse. It would be up to the end user to determine suitability. See the links below to the supplier datasheet and product page, respectively:

      Datasheet
      https://www.atlasantibodies.com/api/print_datasheet/HPA016815.pdf

      Product page
      https://www.atlasantibodies.com/products/antibodies/primary-antibodies/triple-a-polyclonals/zbtb20-antibody-hpa016815/

      Helpful?

  2. Does the antibody anti-Zbtb20 (HPA016815) has reactivity towards mouse samples? Or only human? Thank you very much

    1 answer

    1. The antigen to produce this antibody is product APREST73760. The mouse sequence is 98% identical to the human sequence. According to the validation by the Human Protein Atlas (HPA) in mouse brain tissue, it is likely able to recognize the mouse anti-Zbtb20 protein. This information, along with the complete validation records for this Prestige Antibody® is provided by the HPA through their website. A hyperlink at the top of our product detail page with the Human Protein Atlas Number will direct you there.

      Helpful?

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