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Merck

H6647

Sigma-Aldrich

L-组氨醇 二盐酸盐

≥98% (TLC)

别名:

β-氨基咪唑-4-丙醇 二盐酸盐, (S)-2-氨基-3-(4-咪唑基)丙醇 二盐酸盐

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10 MG
$55.60
1 G
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5 G
$1,090.00

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10 MG
$55.60
1 G
$276.00
5 G
$1,090.00

About This Item

经验公式(希尔记法):
C6H11N3O · 2HCl
CAS号:
分子量:
214.09
Beilstein:
3914853
EC 号:
MDL编号:
UNSPSC代码:
12352209
PubChem化学物质编号:
NACRES:
NA.32

$55.60


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产品名称

L-组氨醇 二盐酸盐, ≥98 (TLC)

方案

≥98% (TLC)

表单

powder

颜色

white to off-white

mp

198-201 °C (dec.) (lit.)

应用

cell analysis

SMILES字符串

Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1

InChI

1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6;;/h2,4-5,10H,1,3,7H2,(H,8,9);2*1H/t5-;;/m0../s1

InChI key

FRCAFNBBXRWXQA-XRIGFGBMSA-N

基因信息

human ... HRH1(3269)
mouse ... HRH1(15465)
rat ... HRH1(24448)

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应用

L-组氨醇二盐酸盐已用于:
  • 作为尿液代谢物分析的试剂[1]
  • 制备 DT40 敲除细胞,在 1 mg/mL 组氨酸中选择细胞[2]
  • 在 HepG2 细胞中诱导氨基酸剥夺[3]

生化/生理作用

组胺的前体;合成蛋白质的可逆抑制剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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David G Meckes et al.
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The conserved UL16 tegument protein of herpes simplex virus exhibits dynamic capsid-binding properties with a release mechanism that is triggered during initial virus attachment events. In an effort to understand the capsid association and subsequent release of UL16, we sought
R C Warrington
Biochemistry and cell biology = Biochimie et biologie cellulaire, 70(5), 365-375 (1992-05-01)
Human cancer chemotherapy is limited by two major problems: the failure of commonly used anticancer drugs to act against tumor cells in a specific manner and the ability of malignant cells to resist killing by antineoplastic agents. Experimentally, both of
Fouzia Sadiq et al.
Nutrition & metabolism, 5, 5-5 (2008-02-14)
Intravenous infusions of glucose and amino acids increase both nitrogen balance and muscle accretion. We hypothesised that co-infusion of glucose (to stimulate insulin) and essential amino acids (EAA) would act additively to improve nitrogen balance by decreasing muscle protein degradation
Ravi K Dinesh et al.
European journal of immunology, 50(3), 380-395 (2019-12-11)
Secondary diversification of the Ig repertoire occurs through somatic hypermutation (SHM), gene conversion (GCV), and class switch recombination (CSR)-three processes that are initiated by activation-induced cytidine deaminase (AID). AID targets Ig genes at orders of magnitude higher than the rest
Sebastian Alers et al.
Autophagy, 7(12), 1423-1433 (2011-10-26)
Under normal growth conditions the mammalian target of rapamycin complex 1 (mTORC1) negatively regulates the central autophagy regulator complex consisting of Unc-51-like kinases 1/2 (Ulk1/2), focal adhesion kinase family-interacting protein of 200 kDa (FIP200) and Atg13. Upon starvation, mTORC1-mediated repression

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