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Merck

H0267

Sigma-Aldrich

亚铁稳定化血红蛋白 A0

lyophilized powder

别名:

Hemoglobin A0 Ferrous Stabilized, Hemoglobin-A0

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About This Item

CAS号:
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
eCl@ss:
42030116
NACRES:
NA.61

生物源

human

品質等級

化驗

97-100% (agarose gel electrophoresis)

形狀

lyophilized powder

技術

immunofluorescence: suitable

溶解度

H2O: soluble 20 mg/mL

適合性

suitable for electrophoresis and chromatography standard

UniProt登錄號

儲存溫度

−20°C

基因資訊

human ... HBB(3043)

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一般說明

血红蛋白是红细胞的主要成分,也是红细胞呈现红色的原因。它在红细胞中的正常浓度为34%。由于它能够将氧从肺部输送到身体组织,促进二氧化碳的返回转运,因此血红蛋白是脊椎动物最重要的呼吸蛋白。
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).

應用

亚铁稳定化人血红蛋白A0可用于:
  • 作为非荧光吸收剂制备仿组织模型
  • 了解冠状动脉斑块内出血如何引发新型抗动脉粥样硬化巨噬细胞表型
  • 研究血红蛋白(Hb)A0、HbA2和HbS对HbF测定的干扰

血红蛋白A0用于了解冠状动脉斑块内出血如何引发新型抗动脉粥样硬化巨噬细胞表型。它可用于时间分辨免疫荧光法测定胎儿血红蛋白。

生化/生理作用

血红蛋白(Hb)编码基因的变异会导致血红蛋白病(如地中海贫血)和非典型结构变异(如Hb Lepore和HbE)。

包裝

包装规格标示出通过 Drabkin, D.L., J. Biol. Chem., 164, 703 (1946) 中介绍的方法测定的血红蛋白含量。

重構

用缓冲液复原时,可得到 >85% 的亚铁血红蛋白。

免責聲明

供研究使用。在法国,在用于科研目的时(包括进口和出口活动(《公共健康法》第L 1211-1条,第2节))该产品为管制品。购买者(即最终用户)需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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