G8293

Galanin (2-11) porcine, rat

≥97% (HPLC), lyophilized powder

• 经验公式（希尔记法）: C₅₄H₈₁N₁₃O₁₄
• 分子量: 1136.30
• MDL编号: MFCD05664726
• UNSPSC代码: 12352209
• PubChem化学物质编号: 329799978
• NACRES: NA.32

属性

• 生物来源: synthetic
• 质量水平: 200
• 方案: ≥97% (HPLC)
• 表单: lyophilized powder
• 组成: Peptide content, ≥65%
• UniProt登记号: P10683
• 储存温度: −20°C
• SMILES字符串: CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc2c[nH]c3ccccc23)[C@@H](C)O)C(N)=O
• InChI: 1S/C54H81N13O14/c1-26(2)17-37(46(57)73)62-49(76)38(18-27(3)4)63-51(78)40(20-31-13-15-33(70)16-14-31)61-44(72)24-59-47(74)29(7)60-53(80)42(25-68)66-52(79)41(22-43(56)71)64-50(77)39(19-28(5)6)65-54(81)45(30(8)69)67-48(75)35(55)21-32-23-58-36-12-10-9-11-34(32)36/h9-16,23,26-30,35,37-42,45,58,68-70H,17-22,24-25,55H2,1-8H3,(H2,56,71)(H2,57,73)(H,59,74)(H,60,80)(H,61,72)(H,62,76)(H,63,78)(H,64,77)(H,65,81)(H,66,79)(H,67,75)/t29-,30+,35-,37-,38-,39-,40-,41-,42-,45-/m0/s1
• InChI key: SUJPPMXJCZETOA-ZKEPBWIVSA-N
• 基因信息: rat ... Gal(29141)

说明

Amino Acid Sequence

Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-NH2

一般描述

Galanin (2-11) is a galanin receptor type 2 agonist.[1][2]

生化/生理作用

Studies in mice show that injection of galanin (2-11) has anticonvulsant activity in seizure affected animals with an intact DR (dorsal root)–hippocampal serotonergic profile, and has no effect in animals with absent 5-HT (hydroxytryptamine) profile.[1]

其他说明

Lyophilized from 0.1% TFA in H2O

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable
• 个人防护装备: Eyeshields, Gloves, type N95 (US)