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Merck

G7000

Sigma-Aldrich

α- D -葡萄糖 1-磷酸盐 二钠盐 水合物

≥97% (Enzymatic Purity, anhydrous)

别名:

α-D-葡吡喃糖-1-磷酸, 山梨醇酯

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1 G
$89.20
5 G
$117.00
10 G
$226.00
25 G
$491.00
100 G
$1,470.00

$89.20


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变更视图
1 G
$89.20
5 G
$117.00
10 G
$226.00
25 G
$491.00
100 G
$1,470.00

About This Item

线性分子式:
C6H11O9PNa2 · xH2O
CAS号:
分子量:
304.10 (anhydrous basis)
EC 号:
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

$89.20


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生物来源

synthetic

质量水平

方案

≥97% (Enzymatic Purity, anhydrous)

表单

powder

杂质

≤0.1 mol % glucose
≤0.5 mol % α-D-glucose 1,6-diphosphate

颜色

white

溶解性

water: 50 mg/mL, clear, colorless

痕量阳离子

Na: 13.5-16.7% (anhydrous)

应用

agriculture

储存温度

−20°C

SMILES字符串

[Na+].[Na+].[H]O[H].OC[C@H]1O[C@H](OP([O-])([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13O9P.2Na.H2O/c7-1-2-3(8)4(9)5(10)6(14-2)15-16(11,12)13;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6-;;;/m1.../s1

InChI key

YWAUQXHOCBBYLP-FBNUBEQJSA-L

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一般描述

α-D-葡萄糖 1-磷酸在磷酸葡萄糖变位酶作用下转化为 D-葡萄糖-6-磷酸。

生化/生理作用

Glucose-1-phosphate (G1P) is produced from glycogen during glycogenolysis by the actions of glycogen phosphorylase. Conversion to glucose-6-phosphate (G6P) by phosphoglucomutase allows for entry of the glucose molecule into metabolic pathways such as glycolysis. During glycogenesis, G6P is converted to G1P by the actions of phosphoglucose isomerase.

制备说明

Prepared by a modification of the procedure of McCready, R.M., et al., J. Am. Chem. Soc., 66, 560 (1944).

其他说明

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Jef Van der Borght et al.
Biotechnology journal, 5(9), 986-993 (2010-08-28)
β-D-Glucose-1-phosphate (βGlc1P) is an efficient glucosyl donor for both enzymatic and chemical glycosylation reactions but is currently very costly and not available in large amounts. This article provides an efficient production method of βGlc1P from trehalose and phosphate using the
Ting Yang et al.
The Biochemical journal, 429(3), 533-543 (2010-05-21)
The diverse types of glycoconjugates synthesized by trypanosomatid parasites are unique compared with the host cells. These glycans are required for the parasite survival, invasion or evasion of the host immune system. Synthesis of those glycoconjugates requires a constant supply
Kyra-Melinda Alexacou et al.
Bioorganic & medicinal chemistry, 18(22), 7911-7922 (2010-10-16)
Glycogen phosphorylase (GP) is a promising target for the treatment of type 2 diabetes. In the process of structure based drug design for GP, a group of 15 aromatic aldehyde 4-(β-d-glucopyranosyl)thiosemicarbazones have been synthesized and evaluated as inhibitors of rabbit
Joerg Fettke et al.
Plant physiology, 155(4), 1723-1734 (2010-12-01)
Almost all glucosyl transfer reactions rely on glucose-1-phosphate (Glc-1-P) that either immediately acts as glucosyl donor or as substrate for the synthesis of the more widely used Glc dinucleotides, ADPglucose or UDPglucose. In this communication, we have analyzed two Glc-1-P-related
Achim Dickmanns et al.
Journal of molecular biology, 405(2), 461-478 (2010-11-16)
Nucleotide sugars and the enzymes that are responsible for their synthesis are indispensable for the production of complex carbohydrates and, thus, for elaboration of a protective cellular coat for many organisms such as the protozoan parasite Leishmania. These activated sugars

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