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Merck
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主要文件

G4274

Sigma-Aldrich

Globoside from human erythrocytes

≥95%

别名:

Globotetraosylceramide

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352211

生物来源

human erythrocytes

方案

≥95%

表单

film

官能团

amide
hydroxyl

运输

ambient

储存温度

−20°C

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

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Tetsuya Okuda
International journal of molecular sciences, 21(10) (2020-05-28)
Glycosphingolipids containing very-long-chain fatty acids (VLCFAs) regulate several immune responses, such as cytokine production, immune signaling, and antibody induction. We previously reported that stimulation with an inflammatory mediator, TNF-α, promotes the expression of glycosphingolipids in vascular endothelial cells. The major
Josefine Betz et al.
Biological chemistry, 393(3), 133-147 (2012-06-22)
Membrane microdomain association of the glycosphingolipids (GSLs) globotriaosylceramide (Gb3Cer) and globotetraosylceramide (Gb4Cer), the highly and less effective receptors, respectively, for Shiga toxins (Stxs), is assumed as a functional requirement for Stx-mediated cytotoxicity. In a previous study, we demonstrated predominant localization
Yunsen Li et al.
Glycobiology, 18(2), 158-165 (2007-12-07)
Glycosphingolipids serve as ligands for receptors involved in signal transduction and immune recognition, as exemplified by isoglobotrihexosylceramide, an antigenic ligand for T cell receptors. Mechanistic studies on the regulation of isoglobotrihexosylceramide require biochemical measurement of its lysosomal precursor, isoglobotetraglycosylceramide. It
D H Jones et al.
Biochemistry, 36(28), 8539-8547 (1997-07-15)
Recognition of macromolecules by glycosphingolipids is closely correlated with the nature of the glycolipid carbohydrate; however, it is also thought to be secondarily modulated by the structure of the single fatty acid. In the present work, we sought insight into
Wiebke Storck et al.
Biological chemistry, 393(8), 785-799 (2012-09-05)
Shiga toxins (Stxs) are composed of an enzymatically active A subunit (StxA) and a pentameric B subunit (StxB) that preferentially binds to the glycosphingolipid (GSL) globo\xadtriaosylceramide (Gb3Cer/CD77) and to a reduced extent to globotetraosylceramide (Gb4Cer). The identification of Gb3Cer as

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