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Merck

F7751

Sigma-Aldrich

氟甲睾酮

solid (photosensitive)

别名:

11β,17β-Dihydroxy-9α-fluoro-17α-methyl-4-androsten-3-one, 9α-Fluoro-11β,17β-dihydroxy-17α-methylandrost-4-en-3-one, 9α-Fluoro-11β-hydroxy-17α-methyltestosterone

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About This Item

经验公式(希尔记法):
C20H29FO3
CAS号:
分子量:
336.44
EC號碼:
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:

生物源

Porcine pancreas
bovine milk (other parts like skeletal muscle/bile/bone/connective tissue/skin)
microbial (Mycobacterium sp.)

形狀

solid (photosensitive)

藥物控制

USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada

技術

HPLC: suitable
gas chromatography (GC): suitable

顏色

white

溶解度

H2O: ≤0.5 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 6.4 mg/mL
ethanol: 7.3 mg/mL

應用

forensics and toxicology
veterinary

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

[H][C@@]12CC[C@](C)(O)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)CC[C@]34C

InChI

1S/C20H29FO3/c1-17-8-6-13(22)10-12(17)4-5-15-14-7-9-19(3,24)18(14,2)11-16(23)20(15,17)21/h10,14-16,23-24H,4-9,11H2,1-3H3/t14-,15-,16-,17-,18-,19-,20-/m0/s1

InChI 密鑰

YLRFCQOZQXIBAB-RBZZARIASA-N

基因資訊

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生化/生理作用

Fluoxymesterone is an androgen and anabolic steroid.

象形圖

Health hazard

訊號詞

Warning

危險聲明

防範說明

危險分類

Repr. 2

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Toktam Zohoorian-Abootorabi et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 88, 177-191 (2012-01-06)
This study was designed to examine the interaction of two anti-breast cancer drugs, i.e., fluoxymesterone (FLU) and cyclophosphamide (CYC), with human serum albumin (HSA) using different kinds of spectroscopic, zeta potential and molecular modeling techniques under imitated physiological conditions. The
J E Olson et al.
Cancer, 79(6), 1138-1149 (1997-03-15)
The purpose of this study was to test the role of radiotherapy following total mastectomy, axillary dissection, and adjuvant systemic therapy in the management of operable locally advanced breast carcinoma. After undergoing mastectomy and axillary dissection, 426 patients with locally
Cornelia Fürstenberger et al.
Toxicological sciences : an official journal of the Society of Toxicology, 126(2), 353-361 (2012-01-26)
Anabolic androgenic steroids (AAS) are testosterone derivatives used either clinically, in elite sports, or for body shaping with the goal to increase muscle size and strength. Clinically developed compounds and nonclinically tested designer steroids often marketed as food supplements are
Oscar J Pozo et al.
Journal of mass spectrometry : JMS, 43(3), 394-408 (2007-11-27)
The suitability of liquid chromatography tandem mass spectrometry (LC-MS/MS) and gas chromatography mass spectrometry (GC-MS) for the elucidation of fluoxymesterone metabolism has been evaluated. Electrospray ionization (ESI) and collision induced dissociation (CID) fragmentation in LC-MS/MS and electron impact spectra (EI)
J Aisner et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 13(6), 1443-1452 (1995-06-01)
We sought to compare three doxorubicin-based therapies for metastatic breast cancer for response frequency, time to treatment failure (TTF), and survival. Women with metastatic breast cancer who had measurable disease, required laboratory tests, had received no prior chemotherapy for metastases

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