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Merck
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主要文件

EHU060981

Sigma-Aldrich

MISSION® esiRNA

targeting human WAPL

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About This Item

UNSPSC代码:
41105324
NACRES:
NA.51

描述

Powered by Eupheria Biotech

质量水平

100

产品线

MISSION®

表单

lyophilized powder

esiRNA cDNA靶序列

CAGAAGAGGCCCAATTTCAAACCAGATATCCAAGAAATTCCGAAGAAACCTAAAGTGGAAGAAGAAAGTACTGGAGATCCTTTTGGATTTGATAGTGATGATGAGTCTCTACCAGTTTCTTCAAAGAATTTAGCCCAGGTTAAGTGTTCCTCTTATTCAGAATCTAGTGAAGCTGCTCAGTTGGAAGAGGTCACTTCAGTACTTGAAGCTAATAGCAAAATTAGTCATGTGGTCGTTGAAGACACTGTCGTTTCTGATAAATGCTTCCCTTTGGAGGACACTTTACTTGGGAAAGAAAAGAGCACAAACCGAATTGTAGAAGATGATGCAAGCATAAGTAGCTGTAATAAATTAATAACTTCAGATAAAGTGGAGAATTTTCATGAAGAACATGAAAAGAATAGTCACCATATTCACAAAAATGCTGATGACAGTACTAAGAAACCCAATGCAGAAACTACAGTGGCTTCTGAAATCAAGGA

基因组数据库 |人类登记号

ENSG00000062650

NCBI登记号

NM_015045

运输

ambient

储存温度

−20°C

基因信息

human ... WAPL(23063) , WAPAL(23063)

相关类别

一般描述

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

法律信息

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
QCS
FQR

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Alexandra M Pinzaru et al.
Genes & development, 34(23-24), 1619-1636 (2020-10-31)
Mutations in the telomere-binding protein POT1 are associated with solid tumors and leukemias. POT1 alterations cause rapid telomere elongation, ATR kinase activation, telomere fragility, and accelerated tumor development. Here, we define the impact of mutant POT1 alleles through complementary genetic
Sheroy Minocherhomji et al.
Nature, 528(7581), 286-290 (2015-12-04)
Oncogene-induced DNA replication stress has been implicated as a driver of tumorigenesis. Many chromosomal rearrangements characteristic of human cancers originate from specific regions of the genome called common fragile sites (CFSs). CFSs are difficult-to-replicate loci that manifest as gaps or

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