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生物源
mouse submaxillary glands
品質等級
產品線
BioReagent
化驗
≥98% (SDS-PAGE)
形狀
lyophilized powder
效力
0.02-2.0 ng/mL EC50
包裝
pkg of 0.1 mg
儲存條件
avoid repeated freeze/thaw cycles
技術
cell culture | mammalian: suitable
雜質
endotoxin, tested
顏色
white
UniProt登錄號
儲存溫度
2-8°C
基因資訊
mouse ... Egf(13645)
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相关类别
一般說明
Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor. It is majorly expressed in kidney, parotid gland and salivary gland.
應用
Epidermal Growth Factor from murine submaxillary gland has been used
- in studying its effects on the development of caustic esophageal stricture in rats
- for preparation of MCF-10A cell line
- for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)
生化/生理作用
Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation. EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes. It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia. EGF plays a major role in the maintenance of hair and skin development.
外觀
Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.
準備報告
Purified by gel filtration and ion-exchange chromatography.
分析報告
The biological activity is measured in a proliferation assay using BALB/MK cells.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
Subcellular localization of epidermal growth factor receptor in human submandibular gland
Journal of Anatomy, 208(5), 595-599 (2006)
High-sensitivity TFA-free LC-MS for profiling histones
Proteomics, 11(16), 3326-3334 (2011)
Expression of epidermal growth factor in human tissues
Virchows Archiv. A, Pathological Anatomy and Histopathology, 418(1), 27-32 (1991)
Effects of caffeic acid phenethyl ester and epidermal growth factor on the development of caustic esophageal stricture in rats
Journal of Pediatric Surgery, 36(10), 1504-1509 (2001)
Epidermal growth factor promotes proliferation of dermal papilla cells via Notch signaling pathway
Biochimie, 127(21), 10-18 (2016)
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