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Merck

C7632

Sigma-Aldrich

斑蝥素

别名:

2,3-二甲基-7-氧杂-双环[2.2.1]庚烷-2,3-二羧酸酐, Hexahydro-3a,7a-dimethyl-4,7-epoxyisobenzofuran-1,3-dione, 六氢-3α,7α-二甲基-4,7-环氧异苯并呋喃-1,3-二酮, 班蝥酸酐

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25 MG
$129.00
100 MG
$380.00
500 MG
$1,450.00

About This Item

经验公式(希尔记法):
C10H12O4
CAS号:
分子量:
196.20
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77

$129.00


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新价格,新优惠!

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颜色

white

mp

215-217 °C (lit.)
215-218 °C

溶解性

DMSO: soluble
ethanol: soluble

SMILES字符串

C[C@]12C3CCC(O3)[C@@]1(C)C(=O)OC2=O

InChI

1S/C10H12O4/c1-9-5-3-4-6(13-5)10(9,2)8(12)14-7(9)11/h5-6H,3-4H2,1-2H3/t5-,6+,9+,10-

InChI key

DHZBEENLJMYSHQ-XCVPVQRUSA-N

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一般描述

斑蝥素是一种由斑蝥产生的有毒的发泡剂。它用于治疗痔疮、溃疡、毒虫和瘰疬性皮肤结核。它可用作壮阳药、堕胎药和兽用利尿剂。[1]

应用

斑蝥素已被用于抑制蛋白磷酸酶2(PP2A)。[2]

生化/生理作用

蛋白磷酸酶 2A 的抑制剂。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

象形图

Skull and crossbones

警示用语:

Danger

危险分类

Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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T I Baskin et al.
Plant physiology, 113(2), 493-502 (1997-02-01)
To investigate molecular mechanisms controlling plant morphogenesis, we examined the morphology of primary roots of Arabidopsis thaliana and the organization of cortical microtubules in response to inhibitors of serine/threonine protein phosphatases and kinases. We found that cantharidin, an inhibitor of
Cécile Segonzac et al.
The EMBO journal, 33(18), 2069-2079 (2014-08-03)
Recognition of pathogen-associated molecular patterns (PAMPs) by surface-localized pattern-recognition receptors (PRRs) activates plant innate immunity, mainly through activation of numerous protein kinases. Appropriate induction of immune responses must be tightly regulated, as many of the kinases involved have an intrinsic
Timothy A Hill et al.
Bioorganic & medicinal chemistry, 15(18), 6126-6134 (2007-07-04)
A range of amines was reacted with norcantharidin (2) to provide the corresponding norcantharimides (9-43). Treatment of norcantharidin with allylamine afforded the corresponding allyl-norcantharimide (20) which was amenable to epoxidation (mCPBA, 22) and subsequent ring opening (MeOH/H(+); 23) or alternatively
Heat Oscillations Driven by the Embryonic Cell Cycle Reveal the Energetic Costs of Signaling
Rodenfels J, et al.
Developmental Cell (2019)
Chie-Hong Wang et al.
International journal of molecular sciences, 23(23) (2022-12-12)
Myeloid zinc finger 1 (MZF1), also known as zinc finger protein 42, is a zinc finger transcription factor, belonging to the Krüppel-like family that has been implicated in several types of malignancies, including glioblastoma multiforme (GBM). MZF1 is reportedly an

商品

ReadyShield® phosphatase and protease inhibitor cocktail FAQ for sample protection in a variety of cell types and tissue extracts, including mammalian, plant, and microbial samples. Our ReadyShield® Protease Inhibitor Cocktail is a non-freezing solution that contains inhibitors with a broad specificity for serine, cysteine, acid proteases and aminopeptidases.

Questions

  1. Come si conserva la polvere C7632 Sigma-Aldrich Cantharid?

    1 answer
    1. This product may be stored at room temperature in powder form.

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