C4743

Monoclonal Anti-Cytochrome P450 3A5 小鼠抗

~2 mg/mL, clone F18 P3 B6, purified immunoglobulin, buffered aqueous solution

• 别名: Anti-CP35, Anti-CYP3A5, Anti-P450PCN3, Anti-PCN3
• 分類程式碼代碼: 12352203

属性

• 生物源: mouse
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: F18 P3 B6, monoclonal
• 形狀: buffered aqueous solution
• 分子量: antigen ~55 kDa
• 物種活性: human
• 濃度: ~2 mg/mL
• 技術: immunohistochemistry: suitable; indirect ELISA: suitable; western blot: 0.5-1.0 μg/mL using human recombinant cytochrome P450 3A5.
• 同型: IgG1
• UniProt登錄號: P20815
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CYP3A5(1577)

说明

特異性

The antibody does not cross react with cytochrome P450 3A4 or 3A7.

免疫原

synthetic peptide corresponding to amino acids 380-389 of human cytochrome P450 3A5.

應用

Monoclonal Anti-Cytochrome P450 3A5 antibody produced in mouse is suitable for:

• immunohistochemistry
• indirect ELISA
• western blotting at a concentration of 0.5-1.0 μg/mL using human recombinant cytochrome P450 3A5

生化／生理作用

Cytochrome P450 enzymes are a super family of heme containing mono-oxygenases that in humans are involved with oxidative metabolism of xenobiotics. This metabolism is the initial step in the biotransformation and elimination of a wide variety of drugs and environmental pollutants from the body. The Cytochrome P450 3A (CYP 3A) family contains several isoforms with the CYP 3A4 isoform contributing most of the family activity and the CYP 3A5, 3A7 and 3A43 being the minor isoforms.

外觀

0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: nwg
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter