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Merck

C4284

Sigma-Aldrich

β-Chloro-D-alanine hydrochloride

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About This Item

线性分子式:
C3H6NO2Cl · HCl
CAS号:
分子量:
160.00
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

化驗

≥98% (TLC)

形狀

powder

溶解度

water: 50 mg/mL, clear to very slightly hazy, colorless

儲存溫度

−20°C

SMILES 字串

Cl.N[C@H](CCl)C(O)=O

InChI

1S/C3H6ClNO2.ClH/c4-1-2(5)3(6)7;/h2H,1,5H2,(H,6,7);1H/t2-;/m1./s1

InChI 密鑰

IENJPSDBNBGIEL-HSHFZTNMSA-N

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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J M Manning et al.
Proceedings of the National Academy of Sciences of the United States of America, 71(2), 417-421 (1974-02-01)
The D- and L-isomers of beta-chloroalanine inhibit the growth of Diplococcus pneumoniae, Streptococcus pyogenes, Bacillus subtilis, and Escherichia coli. With pneumococcus the inhibition by beta-chloro-D-alanine is completely prevented by either D-alanine or D-alanyl-D-alanine, while L-alanine is not effective in preventing
Yuki Ogasawara et al.
Journal of biochemical and biophysical methods, 51(2), 139-150 (2002-06-14)
A highly sensitive method has been developed for the determination of gamma-cystathionase (EC. 4.4.1.1.) activity in rat tissues using beta-chloro-L-alanine as a substrate. This method is based on colorimetry for the determination of pyruvate produced from beta-chloro-L-alanine with the beta-elimination
Jorge Cerbon et al.
Experimental parasitology, 122(2), 106-111 (2009-03-03)
The sphingolipids biosynthesis pathway generates bioactive molecules crucial to the regulation of physiological processes. We have recently reported that DAG (diacylglycerol) generated during sphingomyelin synthesis, plays an important role in PKC (protein kinase C) activation, necessary for the transit through
Arthur J L Cooper et al.
Biochemical pharmacology, 65(2), 181-192 (2002-12-31)
The mitochondrial and cytosolic branched-chain aminotransferases (BCAT(m) and BCAT(c)) are homodimers in the fold type IV class of pyridoxal 5'-phosphate-containing enzymes that also contains D-amino acid aminotransferase and 4-amino-4-deoxychorismate lyase (a beta-lyase). Recombinant human BCAT(m) and BCAT(c) were shown to
Arthur J L Cooper et al.
The Biochemical journal, 368(Pt 1), 253-261 (2002-07-26)
Rat liver mitochondrial aspartate aminotransferase (a homodimer) was shown to catalyse a beta-lyase reaction with three nephrotoxic halogenated cysteine S-conjugates [ S -(1,1,2,2-tetrafluoroethyl)-L-cysteine, S -(1,2-dichlorovinyl)-L-cysteine and S -(2-chloro-1,1,2-trifluoroethyl)-L-cysteine], and less effectively so with a non-toxic cysteine S-conjugate [benzothiazolyl-L-cysteine]. Transamination competes

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