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Merck

C3130

Sigma-Aldrich

Cortisone 21-acetate

≥99%

别名:

17α,21-Dihydroxy-4-pregnene-3,11,20-trione 21-acetate, 21-Acetoxy-4-pregnen-17α-ol-3,11,20-trione, 4-Pregnene-17α,21-diol-3,11,20-trione 21-acetate

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About This Item

经验公式(希尔记法):
C23H30O6
CAS号:
分子量:
402.48
Beilstein:
2067543
EC號碼:
MDL號碼:
分類程式碼代碼:
51111800
PubChem物質ID:
NACRES:
NA.77

生物源

synthetic (organic)

無菌

non-sterile

化驗

≥99%

形狀

powder

mp

237-240 °C (lit.)

溶解度

chloroform: 50 mg/mL, clear, colorless to faintly yellow

運輸包裝

ambient

儲存溫度

room temp

SMILES 字串

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O

InChI

1S/C23H30O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-17,20,28H,4-9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1

InChI 密鑰

ITRJWOMZKQRYTA-RFZYENFJSA-N

基因資訊

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一般說明

Cortisone 21-acetate is a prodrug, which has glucocorticoid and mineralocorticoid properties. It is used as a therapeutic option for glucocorticoid replacement.

應用

Cortisone 21-acetate has been used to study its effects in metastasis and phagocytic activity.

象形圖

Health hazard

訊號詞

Warning

危險聲明

危險分類

Repr. 2

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Replacement therapy in Addison?s disease
Lovaas K and Husebye ES
Expert Opinion on Pharmacotherapy (2003)
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The ability to switch from yeast to hyphal growth is essential for virulence in Candida albicans. The cell surface is the initial point of contact between the fungus and the host. In this work, a free-gel proteomic strategy based on
Immunological mechanisms in metastatic spread and the antimetastatic effects of C. parvum
Jones PD and Castro JE
British Journal of Cancer, 35(5), 519-519 (1977)
Lin Lin et al.
The Journal of infectious diseases, 205(2), 337-347 (2011-11-30)
Activated transfected killer (ATAK) cells are immortal phagocytes transfected with a luminescence reporter that effectively treat lethal infections in neutropenic mice. Their in vivo trafficking, lifespan, and immunogenicity are unknown. Mice were made neutropenic; infected or not with Staphylococcus aureus
Foye's Principles of Medicinal Chemistry (2008)

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