推荐产品
product name
L -肉碱 内盐, synthetic, ≥98%
生物源
synthetic
化驗
≥98%
形狀
powder
顏色
white
mp
197-212 °C (lit.)
應用
cell analysis
detection
SMILES 字串
C[N+](C)(C)C[C@H](O)CC([O-])=O
InChI
1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1
InChI 密鑰
PHIQHXFUZVPYII-ZCFIWIBFSA-N
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應用
L-肉碱内盐已被用作Seahorse XF线粒体应激测定中的测定培养基的组分。它还被口服给予荷瘤小鼠,以研究其对过氧化物酶体增殖物激活受体的调节作用,从而对肝脏炎症反应进行分析。
生化/生理作用
肉碱由赖氨酸生物合成。肉碱可促进脂肪酸转运至线粒体区室中。在骨骼肌和心肌组织中,它充当代谢辅助因子。肉碱可能与支链氨基酸的能量产生有关。
肉毒碱是一种天然存在于大多数哺乳动物组织中的季铵。它在骨骼肌和心脏中参与能量代谢调控,浓度相对较高。它可将葡萄糖代谢由糖酵解转移至糖原储存,并促进长链脂肪酸向线粒体转运,使其在线粒体氧化产生能量。
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
其他客户在看
Food & function, 6(8), 2496-2506 (2015-07-21)
Obesity and dyslipidaemia are metabolic defects resulting from impaired lipid metabolism. These impairments are associated with the development of cardiovascular disease and non-alcoholic fatty liver disease. Correcting the defects in lipid metabolism may attenuate obesity and dyslipidaemia, and reduce cardiovascular
Development of a high-throughput method for real-time assessment of cellular metabolism in intact long skeletal muscle fibre bundles
The Journal of Physiology, 594(24), 7197-7213 (2016)
L-carnitine ameliorates the liver inflammatory response by regulating carnitine palmitoyltransferase I-dependent PPAR? signaling
Molecular Medicine Reports, 13(2) (2015)
Clinica chimica acta; international journal of clinical chemistry, 318(1-2), 51-61 (2002-03-07)
Long-term administration of high oral doses of L-carnitine on the skeletal muscle composition and the physical performance has not been studied in humans. Eight healthy male adults were treated with 2 x 2 g of L-carnitine per day for 3
Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects.
Kidney International, 38(5), 912-918 (1990)
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