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Merck

C0158

Sigma-Aldrich

L -肉碱 内盐

≥98%

别名:

左旋肉毒碱, 维生素 BT

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About This Item

线性分子式:
(CH3)3N+CH2CH(OH)CH2COO-
CAS号:
分子量:
161.20
Beilstein:
4292315
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.79

product name

L -肉碱 内盐, synthetic, ≥98%

生物源

synthetic

化驗

≥98%

形狀

powder

顏色

white

mp

197-212 °C (lit.)

應用

cell analysis
detection

SMILES 字串

C[N+](C)(C)C[C@H](O)CC([O-])=O

InChI

1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/t6-/m1/s1

InChI 密鑰

PHIQHXFUZVPYII-ZCFIWIBFSA-N

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應用

L-肉碱内盐已被用作Seahorse XF线粒体应激测定中的测定培养基的组分。它还被口服给予荷瘤小鼠,以研究其对过氧化物酶体增殖物激活受体的调节作用,从而对肝脏炎症反应进行分析。

生化/生理作用

肉碱由赖氨酸生物合成。肉碱可促进脂肪酸转运至线粒体区室中。在骨骼肌和心肌组织中,它充当代谢辅助因子。肉碱可能与支链氨基酸的能量产生有关。
肉毒碱是一种天然存在于大多数哺乳动物组织中的季铵。它在骨骼肌和心脏中参与能量代谢调控,浓度相对较高。它可将葡萄糖代谢由糖酵解转移至糖原储存,并促进长链脂肪酸向线粒体转运,使其在线粒体氧化产生能量。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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