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Merck
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主要文件

BM0009

Sigma-Aldrich

Avitriptan fumarate

≥98% (HPLC)

别名:

3-[3-[4-(5-Methoxy-4-pyrimidinyl)-1-piperazinyl]propyl]-N-methyl-1H-indole-5-methanesulfonamide (E)-2-butenedioate (1:1), BMS-180048, BMS180048

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About This Item

经验公式(希尔记法):
C22H30N6O3S · C4H4O4
分子量:
574.65
UNSPSC代码:
12352200

质量水平

方案

≥98% (HPLC)

表单

powder

颜色

white to beige

溶解性

DMSO: 5 mg/mL, clear (warmed)

储存温度

room temp

InChI

1S/C22H30N6O3S.C4H4O4/c1-23-32(29,30)15-17-5-6-20-19(12-17)18(13-25-20)4-3-7-27-8-10-28(11-9-27)22-21(31-2)14-24-16-26-22;5-3(6)1-2-4(7)8/h5-6,12-14,16,23,25H,3-4,7-11,15H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+

InChI key

FMXXORRZIQGUIN-WLHGVMLRSA-N

生化/生理作用

Avitriptan fumarate is a serotonin 5HT-1B/1D-receptor agonist with anti-migraine activity.
Avitriptan fumarate is a serotonin 5HT-1B/1D-receptor agonist.

特点和优势

Avitriptan is available through a partnership with Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.

法律信息

Sold for research purposes only under agreement from BMS.

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Barbora Vyhlídalová et al.
International journal of molecular sciences, 21(8) (2020-04-23)
The efforts for therapeutic targeting of the aryl hydrocarbon receptor (AhR) have emerged in recent years. We investigated the effects of available antimigraine triptan drugs, having an indole core in their structure, on AhR signaling in human hepatic and intestinal

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