生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
34 kDa
种属反应性
human
浓度
0.5 mg - 1 mg/mL
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... DBP(1628)
一般描述
Albumin promoter (albumin D-box) D-site binding protein (DBP), a PAR basic region leucine zipper (bZIP) protein, is a transcription factor involved in the diurnal regulation of gene transcription in the brain, liver and kidney. It regulates the expression of proteins such as cholesterol 7 α-hydroxylase P450 gene (CYP7) and kisspeptins (Kiss1).
DBP is known to control the growth of liver cells.
Rabbit polyclonal anti-DBP reacts with bovine, canine, human, mouse, and rat D-site of albumin promoter (albumin D-box) binding proteins.
免疫原
Synthetic peptide directed towards the N terminal region of human DBP
应用
Rabbit Anti-DBP can be used for western blot applications at a concentration of 0.5-5.0μg/ml. It can also be used for immunohistochemistry at 4-8μg/ml, using paraffin-embedded tissues.
Rabbit polyclonal anti-DBP is used to tag D site of albumin promoter (albumin D-box) binding protein for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of D site of albumin promoter (albumin D-box) binding protein in diurnal regulation of gene expression.
生化/生理作用
D-site-binding protein (DBP) is a member of the PAR bZIP (proline and acidic amino acid-rich basic leucine zipper) transcription factor family.
序列
Synthetic peptide located within the following region: PKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGR
外形
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
C R Mueller et al.
Cell, 61(2), 279-291 (1990-04-20)
The full-length cDNA for a transcriptional activator, DBP, that binds to the D site of the albumin promoter has been cloned. DBP belongs to a family of related transcription factors including Fos, Jun, CREB, and C/EBP, which share a conserved
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