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Merck
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主要文件

AV31526

Sigma-Aldrich

Anti-SUPT16H antibody produced in rabbit

IgG fraction of antiserum

别名:

Anti-CDC68, Anti-FACT, Anti-FACTP140, Anti-FLJ10857, Anti-FLJ14010, Anti-FLJ34357, Anti-SPT16/CDC68, Anti-Suppressor of Ty 16 homolog (S. cerevisiae)

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41
价格与库存信息目前不能提供

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

66 kDa

物種活性

rabbit, rat, human, pig, horse, dog

濃度

0.5 mg - 1 mg/mL

技術

western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... SUPT16H(11198)

一般說明

SUPT16H is a transcription factor that interacts with RNF40. This transcription factor mediates structural changes in chromatin during DNA double strand repair.
Rabbit Anti-SUPT16H antibody recognizes bovine, rat, human, zebrafish, mouse, and canine SUPT16H.

免疫原

Synthetic peptide directed towards the N terminal region of human SUPT16H

應用

Rabbit Anti-SUPT16H antibody can be used for western blot assays at a concentration of 1.25μg/ml.

生化/生理作用

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H.

序列

Synthetic peptide located within the following region: ASKKKVEFLKQIANTKGNENANGAPAITLLIREKNESNKSSFDKMIEAIK

外觀

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Vijayalakshmi Kari et al.
Cell cycle (Georgetown, Tex.), 10(20), 3495-3504 (2011-10-28)
Many anticancer therapies function largely by inducing DNA double-strand breaks (DSBs) or altering the ability of cancer cells to repair them. Proper and timely DNA repair requires dynamic changes in chromatin assembly and disassembly characterized by histone H3 lysine 56

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