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A7699
腺苷 5'-三磷酸 二钠盐 水合物
Adenosine 5′-triphosphate disodium salt hydrate
BioXtra, ≥99% (HPLC), from microbial
别名:
ATP 二钠盐
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1 G
$282.00
5 G
$759.00
10 G
$1,410.00
About This Item
经验公式（希尔记法）:
C10H14N5Na2O13P3 · xH2O
CAS号:
分子量:
551.14 (anhydrous basis)
EC號碼:
MDL號碼:
分類程式碼代碼:
41106305
eCl@ss:
32160414
PubChem物質ID:
NACRES:
NA.51
推荐产品
生物源
microbial
品質等級
產品線
BioXtra
化驗
≥99% (HPLC)
形狀
powder
雜質
≤0.1% inorganic P
≤3% solvent content
pKa
(1) 4.0, (2) 6.5
溶解度
H2O: 50 mg/mL, clear, colorless
負離子痕跡
chloride (Cl-): ≤0.05%
正離子痕跡
Al: ≤0.005%
Ca: ≤0.01%
Cu: ≤0.001%
Fe: ≤0.05%
K: ≤0.01%
Mg: ≤0.005%
NH4+: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%
λmax
259 nm
儲存溫度
−20°C
SMILES 字串
O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
InChI
1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI 密鑰
NTBQNWBHIXNPRU-MSQVLRTGSA-L
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相关类别
應用
腺苷5γ-三磷酸腺苷(ATP)是体内能量储存和代谢的中心成分。 ATP应用于许多细胞过程、呼吸、生物合成反应、运动和细胞分裂。ATP是许多激酶的底物，这些激酶参与细胞信号和腺苷酸环化酶(s)，产生第二个信使 cAMP。 ATP提供代谢能量来驱动代谢泵。 ATP在一系列酶促反应中充当辅酶。
生化／生理作用
P2 嘌呤能激动剂；增加 Ca2+-激活的 K+ 通道的活性；ATP-依赖酶系统的底物
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儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Faceshields, Gloves, type N95 (US)
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分析证书(COA)
Lot/Batch Number
其他客户在看
Stefan P Mortensen et al.
The Journal of physiology, 589(Pt 7), 1847-1857 (2011-02-09)
Intraluminal ATP could play an important role in the local regulation of skeletal muscle blood flow, but the stimuli that cause ATP release and the levels of plasma ATP in vessels supplying and draining human skeletal muscle remain unclear. To
Mark W Gorman et al.
American journal of physiology. Heart and circulatory physiology, 299(6), H1981-H1989 (2010-09-21)
The adenine nucleotide hypothesis postulates that the ATP released from red blood cells is broken down to ADP and AMP in coronary capillaries and that ATP, ADP, and AMP act on purinergic receptors on the surface of capillary endothelial cells.
Gabriela Brettas Silva et al.
Frontiers in immunology, 11, 564712-564712 (2020-10-30)
Preeclampsia is a hypertensive and inflammatory pregnancy disorder associated with cholesterol accumulation and inflammation at the maternal-fetal interface. Preeclampsia can be complicated with fetal growth restriction (FGR) and shares risk factors and pathophysiological mechanisms with cardiovascular disease. Cholesterol crystal mediated
Shaima'a Hamarsheh et al.
Nature communications, 11(1), 1659-1659 (2020-04-05)
Oncogenic Ras mutations occur in various leukemias. It was unclear if, besides the direct transforming effect via constant RAS/MEK/ERK signaling, an inflammation-related effect of KRAS contributes to the disease. Here, we identify a functional link between oncogenic KrasG12D and NLRP3
Marc Clement et al.
Arteriosclerosis, thrombosis, and vascular biology, 39(8), 1645-1651 (2019-06-07)
MARK4 (microtubule affinity-regulating kinase 4) regulates NLRP3 (nucleotide-binding oligomerization domain, leucine-rich repeat, and pyrin domain containing 3) inflammasome activation. The aim of the study is to examine the role of MARK4 in hematopoietic cells during atherosclerosis. We show increased MARK4
实验方案
ZIC®-cHILIC is a densely bonded zwitterionic stationary phase with phosphorylcholine functional groups covalently attached to silica.
HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.
相关内容
HILIC separation is an alternative that permits sensitive MS detection and without the use of ion-pair reagents.
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What is the water content of Product A7699, Adenosine 5´-triphosphate disodium salt hydrate (ATP)? Does the formula weight listed on the website include water?
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The formula weight on the website does not include water as the amount of water in the product will vary from lot to lot. The water content for any specific lot will be reported on the Certificate of Analysis for that lot.
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What is the solubility of Product A7699, Adenosine 5´-triphosphate disodium salt hydrate (ATP)?
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ATP disodium salt is soluble in water (50 mg/mL), yielding a clear, colorless solution. This solution is mildly acidic (pH approximately 3.5).
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What is the stability of Product A7699, Adenosine 5´-triphosphate disodium salt hydrate (ATP), in solution?
1 answer-
Aqueous solutions of ATP are stable for months when frozen at -15°C and for approximately one week at 0°C. ADP is the first hydrolysis product formed, with additional hydrolysis leading to the formation of AMP. However, ATP solutions are only stable for several hours at 0 °C when dissolved in a trichloroacetic acid solution. In alkaline solution, it rapidly decomposes to inorganic pyrophosphate and adenosine 5'-phosphate even at 0 °C. This information can be found on the product information sheet (under Documents, above.
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