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Merck

A6683

Sigma-Aldrich

L -天冬氨酸 钠盐 一水合物

≥98% (TLC)

别名:

(S)-2-氨基丁二酸 钠盐, L-天冬氨酸钠

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25 G
$91.10
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$236.00
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$1,480.00

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25 G
$91.10
100 G
$236.00
1 KG
$1,480.00

About This Item

线性分子式:
HO2CCH2CH(NH2)CO2Na · H2O
分子量:
173.10
Beilstein:
6101944
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32160406
PubChem化学物质编号:
NACRES:
NA.32

$91.10


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产品名称

L -天冬氨酸 钠盐 一水合物, ≥98% (TLC)

方案

≥98% (TLC)

表单

powder

颜色

white

SMILES字符串

[Na+].[H]O[H].N[C@@H](CC(O)=O)C([O-])=O

InChI

1S/C4H7NO4.Na.H2O/c5-2(4(8)9)1-3(6)7;;/h2H,1,5H2,(H,6,7)(H,8,9);;1H2/q;+1;/p-1/t2-;;/m0../s1

InChI key

PPTHNBYUFXSJPS-JIZZDEOASA-M

基因信息

human ... GRIN2A(2903)
rat ... GRIN2A(14811)

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一般描述

天冬氨酸是非必需氨基酸。[1]L-天冬氨酸是一种二羧基氨基酸,参与神经细胞蛋白的合成。它还会刺激神经细胞膜的去极化。[2]L-天冬氨酸是转氨反应中的胺供体。[3]

应用

L-天冬氨酸钠盐一水合物已用作结晶储备溶液的成分。[4][5]

生化/生理作用

L-天冬氨酸在血脑屏障上的选择性流出控制了脑中L和D天冬氨酸的水平。大脑中L-天冬氨酸水平的增加可导致兴奋性神经毒性。[6]最近的研究突出了L-天冬氨酸的外消旋化是在确定D:L比率之后以估算个体的年龄。[7]
快速突触兴奋的主要神经递质。

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Structural insight into substrate selectivity of Erwinia chrysanthemi l-Asparaginase
Nguyen HA, et al.
Biochemistry, 55(8), 1246-1253 (2016)
Age estimation of living Indian individuals based on aspartic acid racemization from tooth biopsy specimen
Manu Rastogi
Journal of Forensic Sciences, 9(2), 83-90 (2017)
Biocatalysis (2013)
The l-isomer-selective transport of aspartic acid is mediated by ASCT2 at the blood?brain barrier
Kazuhiro Tetsuka
Journal of Neurochemistry, 87(4), 891-901 (2003)
The Biological Effects of Glutamic Acid and Its Derivatives (2012)

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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