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Merck
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主要文件

A6655

Sigma-Aldrich

Aflatoxin B₁−BSA Conjugate

from Aspergillus flavus, powder, hepatotoxic mycotoxin

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About This Item

MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.77
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产品名称

黄曲霉毒素B1−BSA共轭物 来源于黄曲霉,

形狀

powder

品質等級

標籤範圍

8-12 mol Aflatoxin B1 per mol BSA

儲存溫度

2-8°C

一般說明

Aflatoxin B1 is the most toxic aflatoxin.[1] Aflatoxins are hepatotoxic metabolites,[2] that are produced by molds, such as Aspergillus flavus and Aspergillus parasiticus.[3] Aflatoxins contaminate human food and animal feed.[3] They are linked to liver cancer,[4] immune system suppression, reduced growth rates, losses in feed efficiency and death.[3] They are naturally found toxic carcinogens and the most widely known mycotoxins. They mainly contaminate fruits, vegetables and grains.[4]

應用

Aflatoxin B1 is a carcinogenic compound that induces transversion of G to T at codon 249 of the p53 tumor suppressor gene.
Aflatoxin B1-BSA Conjugate from Aspergillus flavus has been used in immunization of mice with phage and synthetic peptide.[5] It is also used as a target molecule in si field-effect transistor (FET) biosensing techniques.[6]

警告

可能致癌。

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)
Morvarid Karamkhani et al.
Environmental monitoring and assessment, 192(7), 472-472 (2020-07-02)
Many workers are exposed to health problems arising from molds, fungi, and their toxins during waste processing. Aflatoxin B1 (AFB1) level in airborne and settled dust, aflatoxin B1-albumin (AFB1-Alb) adduct in serum, liver and kidney biochemical tests, and body redox
Detection of uncharged or feebly charged small molecules by field-effect transistor biosensors
Ah CS, et al.
Biosensors And Bioelectronics, 33(1), 233-240 (2012)
Regional differences in production of aflatoxin B1 and cyclopiazonic acid by soil isolates of Aspergillus flavus along a transect within the United States
Horn BW and Dorner JW
Applied and Environmental Microbiology, 65(4), 1444-1449 (1999)
Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens (2008)

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