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Merck

A6428

Sigma-Aldrich

黄曲霉毒素M1

from Aspergillus flavus

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About This Item

经验公式(希尔记法):
C17H12O7
CAS号:
分子量:
328.27
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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生物来源

Aspergillus flavus

质量水平

表单

film

储存温度

2-8°C

SMILES字符串

[H][C@]12OC=C[C@@]1(O)c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O7/c1-21-9-6-10-13(17(20)4-5-22-16(17)23-10)14-12(9)7-2-3-8(18)11(7)15(19)24-14/h4-6,16,20H,2-3H2,1H3/t16-,17-/m1/s1

InChI key

MJBWDEQAUQTVKK-IAGOWNOFSA-N

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一般描述

Aflatoxins are metabolites of fungus, that are mainly seen in feeds and foods.[1] Aflatoxin M1 is a hydroxylated metabolite of aflatoxin B1.[2] It is liberated in milk,[2] urine and produced in liver after receiving aflatoxin B1.[3]

应用

Aflatoxin M1 has been used as a standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in Brazilian milk and infant formula.[4] It has also been used as standard to investigate the incidence and occurrence of aflatoxin M1 (AFM1) in dairy products produced in Brazil.[5]
Aflatoxin M1 is both a hepatotoxic and hepatocarcinogenic mycotoxin that has been shown to cause immunosuppression in animals.

生化/生理作用

Aflatoxin M1 possesses hepatocarcinogenic properties.[2]

警告

可能致癌。

制备说明

Aspergillus flavus metabolite.

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Carc. 1B - Muta. 1B

储存分类代码

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Nathalie Paniel et al.
Sensors (Basel, Switzerland), 10(10), 9439-9448 (2010-01-01)
We have developed an electrochemical immunosensor for the detection of ultratrace amounts of aflatoxin M(1) (AFM(1)) in food products. The sensor was based on a competitive immunoassay using horseradish peroxidase (HRP) as a tag. Magnetic nanoparticles coated with antibody (anti-AFM(1))
Aflatoxins
Handbook of Secondary Fungal Metabolites (2003)
Aflatoxins
Handbook of Secondary Fungal Metabolites, 545-569 (2003)
Occurrence of aflatoxin M1 in dairy products in Brazil
Iha MH, et al.
Food Control, 22(12), 1971-1974 (2011)
Aflatoxin M1 in milk and distribution and stability of aflatoxin M1 during production and storage of yoghurt and cheese
Iha MH, et al.
Food Control, 29(1), 1-6 (2013)

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