推荐产品
product name
DL-2-氨基-5-膦酰戊酸, solid
形狀
solid
顏色
white
溶解度
0.1 M NaOH: 4 mg/mL
H2O: 5.6 mg/mL
organic solvents: insoluble
SMILES 字串
NC(CCCP(O)(O)=O)C(O)=O
InChI
1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)
InChI 密鑰
VOROEQBFPPIACJ-UHFFFAOYSA-N
基因資訊
rat ... Grik1(29559) , Grin2a(24409) , Grin2b(24410)
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應用
DL-2-氨基-5-膦酰戊酸已用于:
- N-甲基-D-天冬氨酸(NMDA)介导突触灭活
- 用于生长培养基用于抑制神经元网络的电活性
- 用于分离N-甲基-D-天冬氨酸受体(NMDAR)或α-氨基-3-羟基-5-甲基-4-异噁唑丙酸受体(AMPAR)介导电流
- 溶于双蒸水中,与朊蛋白(PrPC)比较其NMDA拮抗作用
生化/生理作用
镇痉;有效的选择性NMDA受体拮抗剂。
注意
吸湿
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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