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Merck
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文件

A4188

Sigma-Aldrich

N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin

≥97% (HPLC), powder

别名:

Ac-IETD-AMC

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About This Item

经验公式（希尔记法）:
C31H41N5O12
分子量:
675.68
MDL號碼:
MFCD01630896
分類程式碼代碼:
12352209
PubChem物質ID:
24890834
NACRES:
NA.32

化驗

≥97% (HPLC)

形狀

powder

顏色

white

溶解度

DMSO/DMF: 1 mg/mL

儲存溫度

−20°C

SMILES 字串

CC[C@H](C)[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C31H41N5O12/c1-6-14(2)26(32-17(5)38)30(46)34-20(9-10-23(39)40)28(44)36-27(16(4)37)31(47)35-21(13-24(41)42)29(45)33-18-7-8-19-15(3)11-25(43)48-22(19)12-18/h7-8,11-12,14,16,20-21,26-27,37H,6,9-10,13H2,1-5H3,(H,32,38)(H,33,45)(H,34,46)(H,35,47)(H,36,44)(H,39,40)(H,41,42)/t14-,16+,20-,21-,26-,27-/m0/s1

InChI 密鑰

ZYTCBVQZQSFKHQ-HGZCCCDHSA-N

基因資訊

human ... CARD8(22900) , CASP8(841) , CASP8AP2(9994) , CFLAR(8837) , GZMB(3002)
mouse ... CFLAR(117279) , GZMB(171528)
rat ... CASP8(12370) , CFLAR(12633) , GZMB(14939) , RGD1561819(502004) , RGD1562700(502007)

Amino Acid Sequence

NAc-Ile-Glu-Thr-Asp-AMC

應用

Fluorogenic substrate for caspase 8 and granzyme B.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Sigma-Aldrich

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