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Merck

A202

Sigma-Aldrich

N6-2-(4-氨基苯基)乙基腺苷

>95%

别名:

APNEA, N-[2-(4-氨基苯基)乙基]-腺苷, N6-2-(4-氨基苯基)乙基腺苷

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About This Item

经验公式(希尔记法):
C18H22N6O4
CAS号:
分子量:
386.41
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:

化驗

>95%

形狀

solid

溶解度

methanol: slightly soluble 0.2 mg/mL
0.1 M HCl: 14 mg/mL
DMSO: soluble
H2O: insoluble

儲存溫度

2-8°C

SMILES 字串

Nc1ccc(CCNc2ncnc3n(cnc23)[C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)cc1

InChI

1S/C18H22N6O4/c19-11-3-1-10(2-4-11)5-6-20-16-13-17(22-8-21-16)24(9-23-13)18-15(27)14(26)12(7-25)28-18/h1-4,8-9,12,14-15,18,25-27H,5-7,19H2,(H,20,21,22)/t12-,14-,15-,18-/m1/s1

InChI 密鑰

XTPOZVLRZZIEBW-SCFUHWHPSA-N

生化/生理作用

有效的、非选择性A3腺苷受体激动剂。

特點和優勢

《受体分类和信号转导》手册的 腺苷受体页有该化合物的介绍。想要浏览手册的其他页面, 请单击此处

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M G Collis et al.
Trends in pharmacological sciences, 14(10), 360-366 (1993-10-01)
The numerous and widespread effects of adenosine provide both an opportunity for the development of novel therapeutic agents acting via adenosine receptors and the challenge of achieving selectivity of action. The feasibility of achieving selectivity is enhanced if receptor subtypes
J R Fozard et al.
British journal of pharmacology, 109(1), 3-5 (1993-05-01)
The cardiovascular effects of N6-2-(4-aminophenyl)ethyladenosine (APNEA), which when radiolabelled with 125I shows high affinity for the newly described adenosine A3 receptor, have been investigated in the angiotensin II-supported circulation of the pithed rat. APNEA induces hypotensive responses which are unaffected
Adenosine A3 receptors: two into one won't go.
A M Carruthers et al.
Trends in pharmacological sciences, 14(8), 290-291 (1993-08-01)

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