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等級
purum
化驗
≥99.0% (HPLC)
光學活性
[α]20/D +88±2°, c = 1% in ethanol
藥物控制
USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada
mp
139-141 °C
SMILES 字串
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(C)=O
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應用
Testosterone acetate was used to prepare thiosemicarbazone ligand and as a standard to analyze the androgenic steroids from cattle hair by LC/MS/MS.
生化／生理作用
Testosterone is a steroid sex hormone that has physiological roles in both sexes. It modulates the development of brain structure and differentiation of neurons during intrauterine development. It activates signaling by androgen receptors that results in the formation of male sex organs, growth of facial hair and muscles.
其他說明
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Michel W F Nielen et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 830(1), 126-134 (2005-11-23)
The abuse of esters of natural androgenic steroids in cattle fattening and sports is hard to control via routine urine testing. The esters are rapidly hydrolysed in vivo into substances which are also endogenously present in urine. In veterinary control
H Miyamoto et al.
Current cancer drug targets, 12(1), 14-22 (2011-11-25)
Unlike prostate and breast cancers, urothelial carcinoma of the urinary bladder is not yet considered as an endocrine-related neoplasm, and hormonal therapy for bladder cancer remains experimental. Nonetheless, there is increasing evidence indicating that nuclear hormone receptor signals are implicated
A Murugkar et al.
Metal-based drugs, 6(3), 177-182 (2008-05-14)
Testosterone acetate thiosemicarbazone (TATSC, 17-beta-hydroxyandrost-4-one acetate thiosemicarbazone) was synthesized and characterized by single crystal X-ray structure determination. The copper and platinum complexes of this steroid derivative were synthesized and characterized by spectroscopy and electrochemiatry. The in vitro activity of these
Sex hormones, aging, and Alzheimer's disease.
Barron AM, Pike CJ.
Frontiers in Bioscience, 4, 976-997 (2012)
Jaroslava Durdiakova et al.
Acta neurobiologiae experimentalis, 71(4), 434-454 (2012-01-13)
Testosterone is a steroid sex hormone with an important role in the physiology in both sexes. It is involved in the development of morphological and functional parameters of the body via multiple molecular mechanisms. Intensive research focused on testosterone reveals
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