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Merck

73677

Sigma-Aldrich

4-硝基苯基 β-D-葡糖苷酸

β-glucuronidase substrate, chromogenic, ≥99.0% (TLC), powder or crystals, suitable as substrate for β-glucuronidase test

别名:

4-硝基苯基-β-D-吡喃葡萄糖醛酸, PNPG

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About This Item

经验公式(希尔记法):
C12H13NO9
CAS号:
分子量:
315.23
Beilstein:
1438576
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:
NACRES:
NA.32

product name

4-硝基苯基 β-D-葡糖苷酸, ≥99.0% (TLC)

化驗

≥99.0% (TLC)

形狀

powder or crystals

光學活性

[α]20/D −102±3°, c = 1% in ethanol

雜質

≤0.05% free 4-nitrophenol
≤7% water

溶解度

H2O: 0.1 g/mL, clear, faintly yellow

適合性

suitable as substrate for β-glucuronidase test

儲存溫度

−20°C

SMILES 字串

O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)[N+]([O-])=O

InChI

1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-3-1-5(2-4-6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1

InChI 密鑰

QSUILVWOWLUOEU-GOVZDWNOSA-N

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應用

4-硝基苯基β-D-葡萄糖醛酸苷用于测定尿液样本中β-葡萄糖醛酸苷酶的活性,盲肠内容物消化物细菌和牛肝中β-葡萄糖醛酸苷酶的活性。 也用来研究苦味叶下珠提取物对β-葡萄糖醛酸苷酶的抑制作用。

基底

用于 β-葡萄糖醛酸酶(GUS)基因检测的显色底物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Synthesis of Glycaro-1, 5-lactams and Tetrahydrotetrazolopyridine-5-carboxylates: Inhibitors of beta-D-Glucuronidase and alpha-L-Iduronidase
Pabba J, et al.
Helvetica Chimica Acta, 89(4), 635-666 (2006)
Effect of tobacco smoking on albumin concentration and beta-glucuronidase activity in urine of smelters
Bizonn A, et al.
Przegla?d Lekarski, 71(11), 581-584 (2014)
Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
El-Arab AME, et al.
BMC Complementary and Alternative Medicine, 6(1), 6-6 (2006)
M F Massenti et al.
Bollettino dell'Istituto sieroterapico milanese, 60(1), 26-30 (1981-01-01)
Beta-glucuronidase activity has been investigated in 1,221 Enterobacteriaceae strains. The test, using p-nitrophenyl-beta-D-glucuronide (pNPGlcU) agar culture, can be included easily in the routine Enterobacteriaceae biochemical assays. The test is discriminating for Enterobacteriaceae genera and species and useful for identification of
beta-Glucuronidase Inhibitory Effect of Phenolic Constituents from Phyllanthus amarus.
Joshi CS and Sanmuga Priya E
Pharmaceutical biology, 45(5), 363-365 (2007)

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