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Merck
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73361

Sigma-Aldrich

Bis[2-(N-succinimidyl-oxycarbonyloxy)ethyl] sulfone

≥97.0% (CHN)

别名:

BSOCOES

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About This Item

经验公式（希尔记法）:
C14H16N2O12S
CAS号:
57683-72-4
分子量:
436.35
Beilstein:
1521053
EC號碼:
260-904-8
MDL號碼:
MFCD00047123
分類程式碼代碼:
12352200
PubChem物質ID:
57652476

化驗

≥97.0% (CHN)

反應適用性

reagent type: cross-linking reagent

mp

169-173 °C

儲存溫度

−20°C

SMILES 字串

O=C1CCC(=O)N1OC(=O)OCCS(=O)(=O)CCOC(=O)ON2C(=O)CCC2=O

InChI

1S/C14H16N2O12S/c17-9-1-2-10(18)15(9)27-13(21)25-5-7-29(23,24)8-6-26-14(22)28-16-11(19)3-4-12(16)20/h1-8H2

InChI 密鑰

XUDGDVPXDYGCTG-UHFFFAOYSA-N

其他說明

Homobifunctional crosslinking reagent for proteins[1][2][3]; cross-linking reagents used as molecular rulers[4]

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
1436775V
1436775
448762/1

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E Antonian et al.
European journal of biochemistry, 145(3), 511-517 (1984-12-17)
Calf brain plain synaptic vesicle proteins have been cross-linked with bis[2-(succinimidooxycarbonyloxy)ethyl] sulfone, a homobifunctional, cleavable reagent, as well as with N-hydroxysuccinimidyl 4-azidobenzoate, a photosensitive, heterobifunctional reagent. These results demonstrate the generality of a recent report that synaptic vesicle proteins can
J Shin et al.
The Journal of biological chemistry, 260(23), 12822-12827 (1985-10-15)
Both of the alpha and beta subunits of intact human follitropin (FSH) were radioiodinated with 125I-sodium iodide and chloramine-T and could be resolved on sodium dodecyl sulfate-polyacrylamide gels. Radioiodinated FSH was affinity-cross-linked with a cleavable (nondisulfide) homobifunctional reagent to its
P Gourlet et al.
Journal of receptor research, 11(5), 831-848 (1991-01-01)
Cross-linking of [125I]helodermin to human SUP-T1 lymphoblasts with bis[2-(succinimidooxycarbonyloxy)ethyl]sulfone (BSOCOES) revealed a 63 K binding protein. This cross-linking was inhibited by helodermin and VIP. In cells submitted for 3-4 days to 0.2 microgram/ml tunicamycin, the Mr of an increasing proportion
Z Bouizar et al.
European journal of biochemistry, 155(1), 141-147 (1986-02-17)
We have characterized the binding parameters of renal receptors (Scatchard analysis revealed the presence of two binding sites: site I, Ka1 = 1.29 X 10(9) M-1, number of binding sites = 9.9 X 10(6)/micrograms protein; site II, Ka2 = 0.93
M B Brenner et al.
Cell, 40(1), 183-190 (1985-01-01)
Bifunctional cross-linking reagents DSP, DSS, and BSOCOES were used to cross-link 125I-surface-labeled viable T lymphocytes. The cross-linked cells were solubilized in Nonidet-P40, immunoprecipitated with anti-Ti (monoclonal antibody T40/25) or anti-T3 (monoclonal antibodies UCHT-1 or OKT3), and analyzed by SDS-PAGE. With
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