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60178

Sigma-Aldrich

氰化钾

BioUltra, ≥98.0% (AT)

别名:

KCN, Potassium salt of hydrocyanic acid

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About This Item

线性分子式:
KCN
CAS号:
151-50-8
分子量:
65.12
Beilstein:
3593645
EC號碼:
205-792-3
MDL號碼:
MFCD00011397
分類程式碼代碼:
12352302
PubChem物質ID:
57651730
NACRES:
NA.25
产品60178是客户指定产品，不在网上销售。 联系技术服务部门

生物源

synthetic

品質等級

200

產品線

BioUltra

化驗

≥98.0% (AT)

形狀

crystalline

雜質

insoluble matter, passes filter test

pH值

11.0-13.0 (25 °C, 1 M in H2O)

mp

634 °C (lit.)

溶解度

H2O: 1 M at 20 °C, clear, colorless

負離子痕跡

chloride (Cl-): ≤200 mg/kg
sulfate (SO42-): ≤400 mg/kg
sulfide (S2-): ≤5 mg/kg
thiocyanate (SCN-): ≤100 mg/kg

正離子痕跡

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤50 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤100 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤5000 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

&lambda ；

1 M in H2O

紫外吸收

λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.03

SMILES 字串

[K]C#N

InChI

1S/CN.K/c1-2;

InChI 密鑰

YUZRZFQHUCKACF-UHFFFAOYSA-N

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應用

Potassium cyanide is use to inhibit oxidative phosphorylation reactions in a wide variety of biological systems and applications.

其他說明

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research
Blocks electron transport to oxygen via cytochrome oxidase, hence employed in the determination of succinate dehydrogenase in submitochondrial particles by preventing substantial loss of succinate by electron flux to O2[1][2]

訊號詞

Danger

危險分類

Acute Tox. 1 Oral - Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - Met. Corr. 1 - STOT RE 1

標靶器官

Thyroid

安全危害

EUH032

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCL8700
BCCH3565
BCCC6860
BCCC5573
BCBT2916

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Pascaline Clerc et al.
Journal of bioenergetics and biomembranes, 39(2), 158-166 (2007-04-21)
We have studied the effect of nitric oxide (NO) and potassium cyanide (KCN) on oxidative phosphorylation efficiency. Concentrations of NO or KCN that decrease resting oxygen consumption by 10-20% increased oxidative phosphorylation efficiency in mitochondria oxidizing succinate or palmitoyl-L-carnitine, but
EPR and other properties of succinate dehydrogenase.
T Ohnishi et al.
Methods in enzymology, 53, 483-495 (1978-01-01)
Mammalian succinate dehydrogenase.
B A Ackrell et al.
Methods in enzymology, 53, 466-483 (1978-01-01)
Yudong Wang et al.
The Journal of biological chemistry, 285(39), 29834-29841 (2010-07-29)
Fatty acid β-oxidation (FAO) and oxidative phosphorylation (OXPHOS) are key pathways involved in cellular energetics. Reducing equivalents from FAO enter OXPHOS at the level of complexes I and III. Genetic disorders of FAO and OXPHOS are among the most frequent
Vikhyat S Bebarta et al.
Annals of emergency medicine, 64(6), 612-619 (2014-04-22)
Hydroxocobalamin is a Food and Drug Administration-approved antidote for cyanide poisoning. Cobinamide is a potential antidote that contains 2 cyanide-binding sites. To our knowledge, no study has directly compared hydroxocobalamin with cobinamide in a severe, cyanide-toxic large-animal model. Our objective
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Questions

  1. Hello, please can this type be used for laboratory experiments on experimental rodents 

    1 answer

    1. Product No. 60178 is not intended for live animal testing.

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