Unfortunately, the solution stability of this product is not determined. It is recommended to use freshly prepared solutions.
描述
non-ionic
表单
paste
组成
free macrogoly% (27.0 - 39.0 g/100g (%))
杂质
acetic acid (≤ 0.5 g/100g (%))
water (≤ 0.5 g/100g (%))
≤0.05% acetic acid
≤0.05% water
≤1 mg/kg ethylene oxide ((ppm))
≤1 mg/kg ethylene oxide
≤1 mg/kg nickel ((ppm))
≤1 mg/kg nickle
≤10 mg/kg dioxane ((ppm))
≤10 mg/kg dioxane
≤10 mg/kg heavy metals
≤620 mg/kg Diethylene glycol
≤620 mg/kg diethylene glycol ((ppm))
≤620 mg/kg ethylene glycol ((ppm))
≤620 mg/kg ethylene glycol
<10 mg/kg heavy metals ((ppm))
灼烧残渣
(≤ 0.3 g/100g (%))
pH值（酸碱度）
5.0-7.0 (1 g/10 mL in H2O)
mp
25 - 30 °C (77 - 86 °F)
酸值
≤1.0 mg KOH/g
羟基值
90‑110 mg KOH/g
碘值
≤2.0 g I2/100 g
过氧化值
≤3.0 meq/kg
皂化值
53‑63 mg KOH/g
溶解性
water: 200 g/L at 30 °C (86 °F)
密度
1.048 g/cm3 at 20 °C (68 °F)
1.03 g/cm3 at 60 °C (140 °F)
痕量阴离子
<1 ppm (Ethylene Oxide)
<10 ppm (Dioxane)
痕量阳离子
Ni: <1 ppm
heavy metals: <10 ppm
应用
sample preservation
SMILES字符串
C(CCCCC(CCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)O)CCCCC(=O)O
InChI
1S/C47H94O19/c48-15-17-53-19-21-55-23-25-57-27-29-59-31-33-61-35-37-63-39-41-65-43-45-66-44-42-64-40-38-62-36-34-60-32-30-58-28-26-56-24-22-54-20-18-52-16-11-7-6-9-13-46(49)12-8-4-2-1-3-5-10-14-47(50)51/h46,48-49H,1-45H2,(H,50,51)
InChI key
CYAMZYIUAHNTBO-UHFFFAOYSA-N
一般描述
聚乙二醇12羟基硬脂酸酯是一种不依赖pH值的非离子表面活性剂，是一种有效的增溶剂和乳化剂。它可溶于水介质和极性有机溶剂，但不溶于非极性溶剂。其结构为12-羟基硬脂酸（亲脂部分）和聚乙二醇（亲水部分）。
应用
- 聚乙二醇12羟基硬脂酸酯已用于：
- 溶解于地塞米松（DEX），以将其腹腔注射到小鼠体内，测试其握力，进而测量肌肉力量
- 以罗氟司特制剂治疗家兔和豚鼠，以研究臭氧诱导的剧烈咳嗽(hypertussive)反应的机制和药理敏感性
- 溶解非奈利酮，以进行口服应用的体内研究
生化/生理作用
聚乙二醇12羟基硬脂酸酯(12-Hydroxy-octadecanoic acid polymer with α-hydro-ω-hydroxypoly(oxy-1,2-ethanediyl))主要用作肠外和口服制剂的增溶剂。它是化合物的体外筛选和体内疗效研究的首选。聚乙二醇12羟基硬脂酸酯还因其增溶特性和安全性，可用于眼科、大分子、栓剂和蛋白质制剂中。通常可形成10-15纳米的胶束。聚乙二醇12羟基硬脂酸酯可用于开发微乳液IV制剂(micro-emulsion IV formulations)。
法律信息
Solutol is a registered trademark of BASF SE
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Hi how do you store solutol ? at RT, it solidifies
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Hi, What is the recommended storage condition for Kolliphor HS 15 and what is the expected shelf life corresponding the storage condition? Thank you!
1 answer-
This product can be stored at room temperature. Products that are robust in nature and extremely stable, in the original unopened container, are not assigned an expiration date or retest schedule. These products will have no dating reported on either the label or the Certificate of Analysis.
Products that are not assigned an expiration or retest date are covered by a warranty period of 1 year from the date of product shipment.
Full Product Dating Information may be reviewed at the link below: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/190/408/product-dating-information-ms.pdf
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Hi; please, can i have the spectrum IR of macrogol-15-hydroxystearate (lot BBCH6204); best regard.
1 answer-
The attached brochure and attributes table details the M-Clarity™ Program, and the discriminating quality elements for each product level: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/400/043/clarity-program-brochure-br3925en-mk.pdf
https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/General_Information/2/M-Clarity_attributes_table_mk.pdfThe product is marketed as level M-Clarity™ MQ100, MQ200, or MQ300, and as such, does not offer analytical method information (batch testing information / “for-cost” testing). Such a service is offered on products marketed as M-Clarity™ MQ400, and above. For questions regarding M-Clarity™ Program or other product detail, please navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.
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