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Merck
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主要文件

337M-8

Sigma-Aldrich

TAG-72 (B72.3) Mouse Monoclonal Antibody

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41
价格与库存信息目前不能提供

生物来源

mouse

质量水平

100
500

偶联物

unconjugated

抗体形式

culture supernatant

抗体产品类型

primary antibodies

克隆

B72.3, monoclonal

描述

For In Vitro Diagnostic Use in Select Regions (See Chart)

表单

buffered aqueous solution

种属反应性

human

包装

vial of 0.1 mL concentrate (337M-84)
vial of 0.5 mL concentrate (337M-85)
bottle of 1.0 mL predilute (337M-87)
vial of 1.0 mL concentrate (337M-86)
bottle of 7.0 mL predilute (337M-88)

制造商/商品名称

Cell Marque®

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

同位素/亚型

IgG1κ

控制

lung adenocarcinoma

运输

wet ice

储存温度

2-8°C

可视化

cytoplasmic

一般描述

Anti-B72.3 recognizes a high molecular weight glycoprotein called TAG-72 that is present in human adenocarcinomas and in lesser amounts, non-neoplastic tissues. It has also been found to be useful to distinguish between mesothelioma and adenocarcinoma, however, false positive reactions can occur so results must be interpreted with the utmost caution.

质量


IVD

IVD

IVD

RUO

联系

TAG-72 Positive Control Slides, Product No. 337S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

外形

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

制备说明

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

其他说明

For Technical Service please contact: 800-665-7284 or email: [email protected]

法律信息

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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历史批次信息供参考:

分析证书(COA)

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K G Osteen et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 11(3), 216-220 (1992-07-01)
Compared with the degree of investigation of stage-specific expression of tumor-associated glycoprotein-72 (TAG-72) in fundal endometrium, other regions of the female reproductive tract have not received comparable attention. Regional, cell-type-specific, and temporal differences in estrogen receptor and progesterone receptor distribution
W W Johnston et al.
Human pathology, 17(5), 501-513 (1986-05-01)
Monoclonal antibody B72.3 has been shown to be reactive with a high-molecular-weight glycoprotein complex termed TAG(tumor-associated glycoprotein)-72. By the avidin-biotin immunoperoxidase method, fine needle aspirates and corresponding surgically excised tumor tissues from both malignant and benign tissues were analyzed for
The use of Mab B72.3 in the diagnosis of human carcinoma
Schlom J, et al.
J. Tumor Marker oncol., 2, 95-112 (1987)
A Thor et al.
Cancer research, 46(6), 3118-3124 (1986-06-01)
Murine monoclonal antibody B72.3, prepared against a membrane-enriched extract of human metastatic carcinoma, was reacted with a spectrum of adult and fetal human tissues using avidin-biotin-complex immunohistochemical techniques to evaluate the expression of the reactive tumor associated glycoprotein (TAG)-72 antigen.
David C Chhieng et al.
Human pathology, 34(10), 1016-1021 (2003-11-11)
Ovarian carcinoma has a high mortality rate, because most ovarian carcinomas are detected at a late stage. Traditional therapies, such as surgical debulking and chemotherapy, have not been successful in improving the long-term survival of these patients. Alternative therapies targeting

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