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生物源
rabbit
品質等級
100
500
共軛
unconjugated
抗體表格
Ig fraction of antiserum
抗體產品種類
primary antibodies
無性繁殖
polyclonal
描述
For In Vitro Diagnostic Use in Select Regions (See Chart)
形狀
buffered aqueous solution
物種活性
human
包裝
vial of 0.1 mL concentrate (318A-14)
vial of 0.5 mL concentrate (318A-15)
bottle of 1.0 mL predilute (318A-17)
vial of 1.0 mL concentrate (318A-16)
bottle of 7.0 mL predilute (318A-18)
製造商／商標名
Cell Marque™
技術
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
控制
nerve tissue
運輸包裝
wet ice
儲存溫度
2-8°C
視覺化
cytoplasmic
一般說明
Protein gene product 9.5 (PGP 9.5), also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1), is a 27 kDa protein originally isolated from whole brain extracts. Although PGP 9.5 expression in normal tissues was originally felt to be strictly confined to neurons and neuroendocrine cells, it has been subsequently documented in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. A plethora of mesenchymal neoplasms have demonstrated PGP 9.5 expression.
品質
 IVD |  IVD |  IVD |  RUO |
聯結
PGP9.5 Positive Control Slides, Product No. 318S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
外觀
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
準備報告
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
其他說明
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
法律資訊
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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Lucas K Campbell et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 16(10), 963-969 (2003-10-16)
In non-neoplastic tissues, the expression of protein gene product 9.5 (PGP 9.5), a member of the ubiquitin hydrolase family of proteins, is confined to neural and neuroendocrine cells. Although it has been claimed that PGP 9.5 is a specific marker
G Bassotti et al.
Journal of clinical pathology, 58(9), 973-977 (2005-08-30)
Colonic diverticular disease (diverticulosis) is a common disorder in Western countries. Although its pathogenesis is probably multifactorial, motor abnormalities of the large bowel are thought to play an important role. However, little is known about the basic mechanism that may
M Mahalingam et al.
Journal of cutaneous pathology, 28(6), 282-286 (2001-06-13)
Protein gene product 9.5 (PGP 9.5) is expressed in brain at 20 to 50 times the levels detected in other organs. Immunohistochemical studies reveal this protein is localized to both central and peripheral neurons. Recently, PGP 9.5 is reported to
M Mahalingam et al.
Journal of cutaneous pathology, 33(1), 51-56 (2006-01-31)
Cellular neurothekeoma is a relatively rare, benign cutaneous neoplasm, which usually presents as a solitary papule or nodule involving the head and neck area of young adults. Multiple neurothekeomas have not, to date, been known to occur. We report a
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