11702

杆菌肽

from Bacillus licheniformis, ≥65 IU/mg

• 别名: Altracin, Bacitracin A
• 经验公式（希尔记法）: C₆₆H₁₀₃N₁₇O₁₆S
• CAS号: 1405-87-4
• 分子量: 1422.69
• EC號碼: 215-786-2
• MDL號碼: MFCD00062640
• 分類程式碼代碼: 51282002
• PubChem物質ID: 57646949
• NACRES: NA.85

属性

• 生物源: Bacillus licheniformis
• 品質等級: 200
• 形狀: powder
• 比活性: ≥65 IU/mg
• 顏色: white to pale buff
• 抗生素活性譜: Gram-positive bacteria
• 作用方式: cell wall synthesis | interferes
• 儲存溫度: 2-8°C
• SMILES 字串: [H]N1[C@@H](Cc2cnc[nH]2)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)C3CSC(=N3)C(N)C(C)CC)[C@@H](C)CC)C(=O)N[C@H](CCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H](Cc4ccccc4)C1=O
• InChI: 1S/C66H103N17O16S/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88)/t35?,36-,37-,40-,41+,42+,43-,44+,45-,46-,47+,48?,52?,53-,54-/m0/s1
• InChI 密鑰: CLKOFPXJLQSYAH-RNHDWVCBSA-N

说明

一般說明

Chemical structure: peptide

應用

Bacitracin is used to study disruption of bacterial cell wall synthesis at the level of peptidoglycan biosynthesis and isoprenyl metabolism. It is also used to study the biosynthesis of sterols and squalene.
Bacitracin has been used:

• as a protease inhibitor
• as a control antibiotic
• for the calibration in size exclusion chromatography

生化／生理作用

Bacitracin has been shown to decrease vancomycin-resistant Enterococcus faecium population in intestine.

Peptide antibiotic.
Antimicrobial spectrum: Gram-positive bacteria.
Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate.

包裝

5G, 25 G

其他說明

Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep in a dry place.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)