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04276

Sigma-Aldrich

磷酸钠 二元

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E 339, anhydrous, 98-100.5% (calc. to the dried substance)

别名:

磷酸二钠, 磷酸二钠, 磷酸氢二钠, 磷酸氢钠

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1 KG
$274.00
5 KG
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25 KG
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About This Item

线性分子式:
Na2HPO4
CAS号:
7558-79-4
分子量:
141.96
EC 号:
231-448-7
MDL编号:
MFCD00003496
UNSPSC代码:
12161700
eCl@ss:
38070211
PubChem化学物质编号:
329747909
NACRES:
NA.25

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Agency

meets analytical specifications of BP
meets analytical specifications of Ph. Eur.
meets analytical specifications of USP

质量水平

200

等级

puriss.

方案

98-100.5% (calc. to the dried substance)

表单

powder

质量

meets analytical specification of Ph. Eur., BP, USP, FCC, E 339

杂质

reducing matter, complies
 residual solvents, complies
≤0.001% heavy metals (as Pb)
≤0.002% ammonium (NH4)
≤0.2% water-insoluble matter
≤1% NaH2PO4 (calc. to dried subst.)
≤2.0% pyrophosphate (as Na4P2O7)

缺失

≤1% loss on drying, 105°C, 4h
≤1% loss on drying, 130 °C

pH值（酸碱度）

8.4-9.6 (20 °C, 1%)

pKa (25 °C)

(1) 2.15, (2) 6.82, (3) 12.38 (phosphoric acid)

溶解性

H2O: soluble 8 parts
H2O: very soluble (Hot)
alcohol: insoluble

痕量阴离子

chloride (Cl-): ≤50 mg/kg
fluoride (F-): ≤10 mg/kg
sulfate (SO42-): ≤200 mg/kg

痕量阳离子

As: ≤2 mg/kg
Cd: ≤1 mg/kg
Cu: ≤10 mg/kg
Fe: ≤20 mg/kg
Hg: ≤1 mg/kg
Pb: ≤4 mg/kg
Zn: ≤10 mg/kg

适用性

complies for appearance of solution

SMILES字符串

[Na+].[Na+].[H]OP([O-])([O-])=O
[Na+].[Na+].[H]OP([O-])([O-])=O

InChI

1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2

InChI key

BNIILDVGGAEEIG-UHFFFAOYSA-L

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相关类别

应用

磷酸氢二钠已用于制备磷酸盐缓冲液，该缓冲液可用于X-gal染色。[1]

生化/生理作用

磷酸氢二钠是变性凝胶电泳缓冲液的重要组分。[2] 它能够诱导Sprague-Dawley大鼠的肾小球钙化以及其他肾病综合征。[3]

储存分类代码

13 - Non Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
STBL3786
STBL0558
STBK7510
STBK1775
STBJ7622

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Noriko Tsuchiya et al.
Toxicologic pathology, 32(4), 408-412 (2004-06-19)
To elucidate the nephrotoxicity of phosphate, dibasic sodium phosphate solution was given to Sprague-Dawley rats by daily bolus intravenous administration at concentrations of 0, 1, 25, 250, or 360 mM (0, 1, 28, 284, or 408 mg/kg Na2HPO4) for 14
B Duvillié et al.
Endocrinology, 143(4), 1530-1537 (2002-03-19)
The targeted disruption of the two nonallelic insulin genes in mouse was reported previously to result in intrauterine growth retardation, severe diabetes immediately after suckling, and death within 48 h of birth. We have further used these animals to investigate
Noriko Tsuchiya et al.
Toxicologic pathology, 37(3), 270-279 (2009-02-27)
Sprague-Dawley rats received once daily tail-vein injections of 360 mM dibasic sodium phosphate solution at 8 mL/kg for fourteen or twenty-eight days. Clinical examination revealed persistent proteinuria from three days after the first dosing and thereafter severe proteinuria from eight
Megan A Rees et al.
Journal of proteome research, 14(1), 120-132 (2014-10-21)
Interactions between a host and a bacterial pathogen are mediated by cross-talk between molecules present on, or secreted by, pathogens and host binding-molecules. Identifying proteins involved at this interface would provide substantial insights into this interaction. Although numerous studies have
Samuel Adler et al.
Gastrointestinal endoscopy, 76(6), 1170-1174 (2012-10-03)
Colon capsule endoscopy (CCE) is a noninvasive technique for the detection of colorectal lesions. However, for CCE to be offered as an out-of-clinic procedure, the system needs to automatically alert the patient when to ingest the laxative (booster). We tested
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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