推荐产品
等級
pharmaceutical primary standard
API 家族
osthole
製造商/商標名
EDQM
應用
pharmaceutical (small molecule)
格式
neat
儲存溫度
2-8°C
SMILES 字串
COc1ccc2C=CC(=O)Oc2c1C\C=C(\C)C
InChI
1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3
InChI 密鑰
MBRLOUHOWLUMFF-UHFFFAOYSA-N
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一般說明
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
應用
Osthole EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
生化/生理作用
传统中药 蛇床子的有效成分,具有抗炎、镇痛、降脂等作用。在鹌鹑模型中显著降低脂质蓄积。它对MPP(+)诱导的PC12细胞中细胞毒性的神经保护作用支持使用蛇床子素作为治疗神经退行性疾病的治疗剂。在 HER2 过度表达的乳腺癌细胞中抑制脂肪酸合成酶的表达表明蛇床子素有望成为化疗药物。
包裝
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他說明
Sales restrictions may apply.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Osthole attenuates lipid accumulation, regulates the expression of inflammatory mediators, and increases antioxidants in FL83B cells.
Biomedicine and Pharmacotherapy, 91, 78-87 (2017)
Life sciences, 102(2), 105-110 (2014-03-25)
Osthole, a coumarin derivative, has been used in Chinese medicine and studies have suggested a potential use in treatment of diabetes and cancers. Therefore, we investigated the effects of osthole and other coumarins on GLUT1 activity in two cell lines
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