PHR1636

氮䓬斯汀

Pharmaceutical Secondary Standard; Certified Reference Material

• 别名: 氮卓斯汀 盐酸盐, 4-[(4-氯苯基)甲基] -2-(1-甲基氮杂-4-基)酞嗪-1-酮 盐酸盐, 盐酸氮卓斯汀, 阿斯特林
• 经验公式（希尔记法）: C₂₂H₂₄ClN₃O · HCl
• CAS号: 79307-93-0
• 分子量: 418.36
• MDL编号: MFCD00242783
• UNSPSC代码: 41116107
• PubChem化学物质编号: 329823526
• NACRES: NA.24

属性

• 等级: certified reference material; pharmaceutical secondary standard
• 质量水平: 300
• Agency: traceable to Ph. Eur. Y0000326; traceable to USP 1046158
• API类: azelastine
• CofA: current certificate can be downloaded
• 包装: pkg of 1 g
• 技术: HPLC: suitable; gas chromatography (GC): suitable
• 应用: pharmaceutical (small molecule)
• 包装形式: neat
• 储存温度: 2-30°C
• SMILES字符串: Cl.CN1CCCC(CC1)N2N=C(Cc3ccc(Cl)cc3)c4ccccc4C2=O
• InChI: 1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H
• InChI key: YEJAJYAHJQIWNU-UHFFFAOYSA-N
• 基因信息: human ... HRH1(3269)

说明

一般描述

Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Azelastine Hydrochloride is a long-acting antiallergic and antiasthmatic drug.[1]

应用

Azelastine Hydrochloride may be used as a pharmaceutical secondary reference standard for the determination of azelastine in plasma samples by manual-injection liquid chromatographic method using fluorescence detection.[2]

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

H1 组胺受体拮抗剂；NF-kB 激活剂。

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA5303 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

安全信息

• 象形图: GHS07
• 警示用语：: Warning
• 危险声明: H302
• 预防措施声明: P264 - P270 - P301 + P312 - P501
• 危险分类: Acute Tox. 4 Oral
• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable